Quiroga Martinez David R, Fernández Rubio Gemma, Bonetti Leonardo, Achyutuni Kriti G, Tzovara Athina, Knight Robert T, Vuust Peter
Helen Wills Neuroscience Institute & Department of Psychology and Neuroscience, University of California Berkeley, Berkeley, CA.
Psychology Department, University of Copenhagen, Copenhagen, Denmark.
bioRxiv. 2024 Aug 20:2023.08.15.553456. doi: 10.1101/2023.08.15.553456.
Vividly imagining a song or a melody is a skill that many people accomplish with relatively little effort. However, we are only beginning to understand how the brain represents, holds, and manipulates these musical "thoughts". Here, we decoded perceived and imagined melodies from magnetoencephalography (MEG) brain data (N = 71) to characterize their neural representation. We found that, during perception, auditory regions represent the sensory properties of individual sounds. In contrast, a widespread network including fronto-parietal cortex, hippocampus, basal nuclei, and sensorimotor regions hold the melody as an abstract unit during both perception and imagination. Furthermore, the mental manipulation of a melody systematically changes its neural representation, reflecting volitional control of auditory images. Our work sheds light on the nature and dynamics of auditory representations, informing future research on neural decoding of auditory imagination.
生动地想象一首歌曲或一段旋律是一项许多人相对轻松就能掌握的技能。然而，我们才刚刚开始了解大脑如何表征、保存和操控这些音乐“想法”。在此，我们从脑磁图（MEG）脑数据（N = 71）中解码感知到的和想象中的旋律，以表征它们的神经表征。我们发现，在感知过程中，听觉区域表征单个声音的感官属性。相比之下，一个广泛的网络，包括额顶叶皮层、海马体、基底神经节和感觉运动区域，在感知和想象过程中都将旋律作为一个抽象单元保存。此外，对旋律的心理操控会系统地改变其神经表征，反映出对听觉意象的意志控制。我们的工作揭示了听觉表征的本质和动态变化，为未来关于听觉想象神经解码的研究提供了信息。
