Hashempour-Baltork Fataneh, Farshi Parastou, Mirza Alizadeh Adel, Eskandarzadeh Sevda, Abedinzadeh Solmaz, Azadmard-Damirchi Sodeif, Torbati Mohammadali
Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran.
Food Science Institute, Kansas State University, Manhattan, KS, USA.
Adv Pharm Bull. 2023 Jul;13(3):461-468. doi: 10.34172/apb.2023.060. Epub 2022 Nov 2.
Neurodegenerative diseases are comprise a prominent class of neurological diseases. Generally, neurodegenerative diseases cannot be cured, and the available treatments can only regulate the symptoms or delay the disease progression. Among the several factors which could clarify the possible pathogenesis of neurodegenerative diseases, next to aging as the main risk, the dietary related diseases are the most important. Vegetable oils, which are composed of triacyclglycerols as the main components and several other components in a trace amount, are the main part of our diet. This review aims to study the effect of refined or unrefined vegetable oil consumption as a preventive or aiding strategy to slow or halt the progression of neurodegenerative diseases. In the refining process, owing to the chemical materials or severe temperatures of the refining process, removal of the desirable minor components is sometimes unavoidable and thus a worrisome issue affecting physical and neurological health.
神经退行性疾病是一类突出的神经系统疾病。一般来说,神经退行性疾病无法治愈,现有的治疗方法只能调节症状或延缓疾病进展。在能够阐明神经退行性疾病可能发病机制的几个因素中,除了衰老作为主要风险外,与饮食相关的疾病是最重要的。植物油由三酰甘油作为主要成分和其他几种微量成分组成,是我们饮食的主要部分。本综述旨在研究食用精炼或未精炼植物油作为预防或辅助策略对减缓或阻止神经退行性疾病进展的作用。在精炼过程中,由于精炼过程中使用的化学物质或高温,有时不可避免地会去除一些有益的微量成分,这是一个影响身体健康和神经健康的令人担忧的问题。