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量子点的生物合成及其在癌症和SARS-CoV-2诊断与治疗中的应用

Biosynthesis of Quantum Dots and Their Therapeutic Applications in the Diagnosis and Treatment of Cancer and SARS-CoV-2.

作者信息

Moetasam Zorab Musa, Mohammadjani Navid, Ashengroph Morahem, Alavi Mehran

机构信息

Department of Physics, University of Halabja, Kurdistan Region, Iraq.

Department of Biological Science, Faculty of Science, University of Kurdistan, Sanandaj, Kurdistan, Iran.

出版信息

Adv Pharm Bull. 2023 Jul;13(3):411-422. doi: 10.34172/apb.2023.065. Epub 2022 Dec 6.

Abstract

Quantum dots (QDs) are semiconductor materials that range from 2 nm to 10 nm. These nanomaterials (NMs) are smaller and have more unique properties compared to conventional nanoparticles (NPs). One of the unique properties of QDs is their special optoelectronic properties, making it possible to apply these NMs in bioimaging. Different size and shape QDs, which are used in various fields such as bioimaging, biosensing, cancer therapy, and drug delivery, have so far been produced by chemical methods. However, chemical synthesis provides expensive routes and causes and health issues. Therefore, various biological systems such as bacteria, fungi, yeasts, algae, and plants are considered as potent eco-friendly green nanofactories for the biosynthesis of QDs, which are safe. The review aims to provide a descriptive overview of the agents for the of and their biomedical applications for the diagnosis and treatment of cancer and SARS-CoV-2.

摘要

量子点(QDs)是尺寸在2纳米至10纳米之间的半导体材料。与传统纳米颗粒(NPs)相比,这些纳米材料(NMs)更小且具有更多独特性能。量子点的独特性能之一是其特殊的光电性能,这使得这些纳米材料能够应用于生物成像。不同尺寸和形状的量子点被用于生物成像、生物传感、癌症治疗和药物递送等各个领域,到目前为止,它们是通过化学方法制备的。然而,化学合成成本高昂且会引发健康问题。因此,各种生物系统,如细菌、真菌、酵母、藻类和植物,被视为用于生物合成量子点的强大的环保绿色纳米工厂,这些量子点是安全的。本综述旨在对用于量子点生物合成的试剂及其在癌症和SARS-CoV-2诊断与治疗中的生物医学应用进行描述性概述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/10460808/b2f9d6763fa0/apb-13-411-g001.jpg

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