• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非妊娠患者单纯疱疹病毒所致肝炎:阿昔洛韦治疗

Hepatitis due to herpes simplex virus in a nonpregnant patient: treatment with acyclovir.

作者信息

Baxter R P, Phillips L E, Faro S, Hoffman L

出版信息

Sex Transm Dis. 1986 Jul-Sep;13(3):174-6. doi: 10.1097/00007435-198607000-00014.

DOI:10.1097/00007435-198607000-00014
PMID:3764630
Abstract

A previously healthy 19-year-old nonpregnant woman had disseminated infection with herpes simplex virus. The disseminated disease was accompanied by hepatitis. The patient was treated with parenteral acyclovir (5 mg/kg) given every 8 hr. The patient's symptoms resolved after three days of therapy. A review of five similar cases that were observed in healthy nonpregnant and nonimmunosuppressed individuals showed that all five patients died. Thus, rapid diagnosis of this potentially fatal condition is important, and the possible use of acyclovir for such cases should be considered.

摘要

一名既往健康的19岁未孕女性发生了单纯疱疹病毒播散性感染。播散性疾病伴有肝炎。患者接受每8小时一次静脉注射阿昔洛韦(5mg/kg)治疗。治疗三天后患者症状缓解。对在健康未孕且无免疫抑制的个体中观察到的五例类似病例的回顾显示,所有五例患者均死亡。因此,快速诊断这种潜在致命疾病很重要,应考虑对此类病例使用阿昔洛韦的可能性。

相似文献

1
Hepatitis due to herpes simplex virus in a nonpregnant patient: treatment with acyclovir.非妊娠患者单纯疱疹病毒所致肝炎:阿昔洛韦治疗
Sex Transm Dis. 1986 Jul-Sep;13(3):174-6. doi: 10.1097/00007435-198607000-00014.
2
Fulminant, acyclovir-resistant, herpes simplex virus type 2 hepatitis in an immunocompetent woman.一名免疫功能正常女性的暴发性、耐阿昔洛韦的2型单纯疱疹病毒性肝炎
J Clin Microbiol. 2006 Apr;44(4):1584-6. doi: 10.1128/JCM.44.4.1584-1586.2006.
3
Successful Treatment of Herpes Simplex Virus (HSV)-1-associated Hemophagocytic Lymphohistiocytosis (HLH) with Acyclovir: A Case Report and Literature Review.阿昔洛韦成功治疗单纯疱疹病毒1型(HSV-1)相关噬血细胞性淋巴组织细胞增生症(HLH):病例报告及文献综述
Intern Med. 2017 Nov 1;56(21):2919-2923. doi: 10.2169/internalmedicine.8490-16. Epub 2017 Sep 15.
4
Acyclovir for disseminated herpes simplex virus in pregnancy. A case report.阿昔洛韦用于妊娠期播散性单纯疱疹病毒感染。病例报告。
J Reprod Med. 1994 Apr;39(4):311-7.
5
Herpes simplex virus hepatitis causing acute liver dysfunction and thrombocytopenia in pregnancy.单纯疱疹病毒肝炎导致妊娠期急性肝功能障碍和血小板减少症。
Obstet Gynecol. 2005 Nov;106(5 Pt 2):1187-9. doi: 10.1097/01.AOG.0000160481.11517.a0.
6
Recurrent herpes simplex virus hepatitis after liver retransplantation despite acyclovir therapy.尽管使用了阿昔洛韦治疗,但肝再次移植后仍出现复发性单纯疱疹病毒肝炎。
Liver Transpl. 2005 Oct;11(10):1289-94. doi: 10.1002/lt.20567.
7
Acyclovir-resistant chronic cutaneous herpes simplex in Wiskott-Aldrich syndrome.威斯科特-奥尔德里奇综合征中的耐阿昔洛韦慢性皮肤单纯疱疹
Br J Dermatol. 1995 Sep;133(3):475-8. doi: 10.1111/j.1365-2133.1995.tb02682.x.
8
Fulminant hepatitis during herpes simplex virus infection in apparently immunocompetent adults: report of two cases and review of the literature.免疫功能正常的成年人单纯疱疹病毒感染期间的暴发性肝炎:两例报告及文献复习
Clin Infect Dis. 1997 Jun;24(6):1191-4. doi: 10.1086/513646.
9
Disseminated herpes simplex virus infection in an apparently immunocompetent woman.一名看似免疫功能正常的女性发生播散性单纯疱疹病毒感染。
Med J Aust. 1989 Nov 20;151(10):588-90, 592, 594. doi: 10.5694/j.1326-5377.1989.tb101292.x.
10
Disseminated herpes simplex infection in an immunocompromised pregnancy: treatment with intravenous acyclovir.免疫功能低下孕妇的播散性单纯疱疹感染:静脉注射阿昔洛韦治疗。
Am J Perinatol. 1987 Oct;4(4):363-4. doi: 10.1055/s-2007-999809.

引用本文的文献

1
Fatal fulminant herpes simplex hepatitis following surgery in an adult.一名成年人术后发生致命性暴发性单纯疱疹病毒性肝炎。
World J Clin Cases. 2018 Feb 16;6(2):11-19. doi: 10.12998/wjcc.v6.i2.11.
2
Fulminant, acyclovir-resistant, herpes simplex virus type 2 hepatitis in an immunocompetent woman.一名免疫功能正常女性的暴发性、耐阿昔洛韦的2型单纯疱疹病毒性肝炎
J Clin Microbiol. 2006 Apr;44(4):1584-6. doi: 10.1128/JCM.44.4.1584-1586.2006.
3
Herpes simplex-induced fulminant hepatitis in adults: a call for empiric therapy.成人单纯疱疹病毒所致暴发性肝炎:呼吁经验性治疗
Dig Dis Sci. 2000 Dec;45(12):2399-404. doi: 10.1023/a:1005699210816.
4
Fatal herpes simplex hepatitis type 2 in a post-thymectomized adult.
Gastroenterol Jpn. 1993 Apr;28(2):304-11. doi: 10.1007/BF02779235.
5
Herpes latency, meningitis, radiculomyelopathy and disseminated infection.疱疹潜伏、脑膜炎、神经根脊髓病和播散性感染。
Genitourin Med. 1994 Dec;70(6):369-77. doi: 10.1136/sti.70.6.369.
6
Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy.阿昔洛韦。对其抗病毒活性、药代动力学特性及治疗效果的最新综述。
Drugs. 1989 Mar;37(3):233-309. doi: 10.2165/00003495-198937030-00002.