Department of Physical Therapy, Takasaki University of Health and Welfare, 501 Nakaorui-machi, Takasaki, Gunma, 370-0033, Japan.
Department of Rehabilitation, Iwamuro Rehabilitation Hospital, 772-1 Iwamuronsen, Nishikan-ku, Niigata, Niigata, 953-0104, Japan.
J Med Ultrason (2001). 2023 Oct;50(4):551-560. doi: 10.1007/s10396-023-01356-1. Epub 2023 Aug 30.
We examined the association of activities of daily living (ADL), mobility and balance ability, and symptoms of Parkinson's disease (PD) with the masses and amounts of intramuscular non-contractile tissue of the trunk and lower extremity muscles in patients with PD.
The subjects were 11 community-dwelling patients with PD. ADL were assessed using the Functional Independence Measure. Mobility capacity was assessed based on measurement of maximal walking speed and timed up-and-go time, while balance ability was evaluated based on measurement of one-legged stance time. The symptoms of PD were assessed based on measurement of the Hoehn and Yahr stage and Unified Parkinson's Disease Rating Scale. Muscle thickness (MT) and echo intensity (EI) of the trunk and lower extremity muscles were also measured using an ultrasound imaging device.
Partial correlation analysis revealed an association between reduced ADL and increased EI of the lumbar erector spinae muscle; reduced mobility capacity and increased EI of the rectus abdominis and gluteus minimus muscles; and reduced balance ability and decreased MT of the lumbar erector spinae muscle and increased EI of the lumbar erector spinae, semitendinosus, and tibialis posterior muscles. Partial correlation analysis also showed an association between symptoms of severe PD and decreased MT of the tibialis anterior muscles and increased EI of the lumbar erector spinae, gluteus minimus, and tibialis posterior muscles.
The properties of the trunk and lower extremity muscles may be critical for ADL, mobility and balance ability, and symptoms of PD in patients with PD.
我们研究了日常生活活动（ADL）、移动能力和平衡能力以及帕金森病（PD）症状与 PD 患者躯干和下肢肌肉内非收缩组织的质量和数量之间的关系。
研究对象为 11 名居住在社区的 PD 患者。ADL 使用功能独立性测量法进行评估。移动能力基于最大步行速度和计时上下车时间进行评估，而平衡能力则基于单腿站立时间进行评估。PD 的症状通过 Hoehn 和 Yahr 分期和统一帕金森病评定量表进行评估。使用超声成像设备测量躯干和下肢肌肉的肌肉厚度（MT）和回声强度（EI）。
偏相关分析显示，ADL 降低与腰椎竖脊肌 EI 增加有关；移动能力降低与腹直肌和臀小肌 EI 增加有关；平衡能力降低与腰椎竖脊肌 MT 降低和 EI 增加有关。偏相关分析还显示，严重 PD 症状与胫骨前肌 MT 降低和腰椎竖脊肌、臀小肌和胫骨后肌 EI 增加有关。
PD 患者的躯干和下肢肌肉的特性可能对 ADL、移动能力和平衡能力以及 PD 症状至关重要。
