IL-38 在疾病中的新兴作用：全面综述。
The emerging role of IL-38 in diseases: A comprehensive review.
机构信息
Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
School of Forensic Medcine, Zunyi Medical University, Zunyi, Guizhou, China.
出版信息
Immun Inflamm Dis. 2023 Aug;11(8):e991. doi: 10.1002/iid3.991.
INTRODUCTION
Interleukin-38 (IL-38) is a new type of anti-inflammatory cytokine, which is mainly expressed in the immunity-related organs and is involved in various diseases including cardiovascular and cerebrovascular diseases, lung diseases, viral infectious diseases and autoimmune diseases.
AIM
This review aims to detail the biological function, receptors and signaling of IL-38, which highlights its therapeutic potential in related diseases.
CONCLUSION
This article provides a comprehensive review of the association between interleukin-38 and related diseases, using interleukin-38 as a keyword and searching the relevant literature through Pubmed and Web of science up to July 2023.
简介
白细胞介素-38（IL-38）是一种新型抗炎细胞因子，主要在免疫相关器官中表达，参与包括心血管和脑血管疾病、肺部疾病、病毒感染性疾病和自身免疫性疾病在内的多种疾病。
目的
本综述旨在详细阐述 IL-38 的生物学功能、受体和信号通路，突出其在相关疾病中的治疗潜力。
结论
本文通过使用白细胞介素-38 作为关键词，在 Pubmed 和 Web of science 上检索截至 2023 年 7 月的相关文献，对白细胞介素-38 与相关疾病的关系进行了全面综述。
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