Department of Gastroenterology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.
Department of Gastroenterology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.
Hepatobiliary Pancreat Dis Int. 2024 Oct;23(5):458-462. doi: 10.1016/j.hbpd.2023.08.014. Epub 2023 Aug 22.
Acute pancreatitis is a common systemic inflammatory disease, manifested by a spectrum of severity, ranging from mild in the majority of patients to severe acute pancreatitis. Patients with severe acute pancreatitis suffer from severe local and systemic complications and organ failure, leading to a poor prognosis. The early recognition of the severe condition is important to improve prognosis. Obesity has risen in tandem with an increase in the severity of acute pancreatitis in recent years. Studies have revealed that adipose tissue, particularly visceral adipose tissue is associated with the prognosis of acute pancreatitis. This review discussed the role of visceral adipose tissue in obese patients with acute pancreatitis and explored the possible mechanism involved.
急性胰腺炎是一种常见的全身炎症性疾病，其严重程度不一，大多数患者为轻度，少数患者为重症急性胰腺炎。重症急性胰腺炎患者常伴有严重的局部和全身并发症及器官功能衰竭，预后较差。早期识别重症状态对于改善预后非常重要。近年来，随着急性胰腺炎严重程度的增加，肥胖症的发病率也有所上升。研究表明，脂肪组织，尤其是内脏脂肪组织与急性胰腺炎的预后有关。本文综述了内脏脂肪组织在肥胖型急性胰腺炎患者中的作用，并探讨了其可能的作用机制。
