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代谢综合征与急性胰腺炎:现状与未来展望。

Metabolic syndrome and acute pancreatitis: Current status and future prospects.

作者信息

Quan Ying, Yang Xiao-Jun

机构信息

The First Clinical Medical School, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China.

Department of Second Ward of General Surgery, Gansu Province People Hospital, Lanzhou 730000, Gansu Province, China.

出版信息

World J Gastroenterol. 2024 Dec 7;30(45):4859-4863. doi: 10.3748/wjg.v30.i45.4859.

DOI:10.3748/wjg.v30.i45.4859
PMID:39649542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11606369/
Abstract

Rising incidence of a complicated disorder with a multifarious etiology is acute pancreatitis. Growing numbers of cases of acute pancreatitis are linked to obesity, hyperlipidemia, hyperglycemia, hypertension, and other metabolic diseases. Trends driven by better living standards and unhealthy lifestyle choices both in China and abroad. Furthermore common diagnosis for many patients is metabolic syndrome. Predicting the adverse effect of metabolic syndrome on the severity and prognosis of acute pancreatitis is a main focus of present clinical research. Our next studies seek to investigate the fundamental causes of this link and create preventative plans meant to lower the incidence of pancreatitis linked to metabolic syndrome and enhance the prognosis.

摘要

病因多样的复杂病症——急性胰腺炎的发病率正在上升。越来越多的急性胰腺炎病例与肥胖、高脂血症、高血糖、高血压及其他代谢性疾病有关。这一趋势在中国和国外都是由生活水平提高和不健康的生活方式选择所驱动的。此外,许多患者的常见诊断是代谢综合征。预测代谢综合征对急性胰腺炎严重程度和预后的不良影响是当前临床研究的主要重点。我们接下来的研究旨在探究这种关联的根本原因,并制定预防计划,以降低与代谢综合征相关的胰腺炎发病率,改善预后。

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2
Adipokines and their role in acute pancreatitis.脂肪细胞因子及其在急性胰腺炎中的作用。
J Med Biochem. 2024 Jun 15;43(4):512-527. doi: 10.5937/jomb0-47515.
3
Intense and Sustained Alcohol Consumption Associated With Acute Pancreatitis Warrants Early Intervention.与急性胰腺炎相关的大量持续饮酒值得早期干预。
Gastro Hep Adv. 2023 Sep 2;3(1):61-63. doi: 10.1016/j.gastha.2023.08.017. eCollection 2024.
4
Highly functional duodenal stent with photosensitizers enables photodynamic therapy for metabolic syndrome treatment: Feasibility and safety study in a porcine model.带有光敏剂的高功能十二指肠支架实现用于代谢综合征治疗的光动力疗法:猪模型的可行性和安全性研究
APL Bioeng. 2024 Jul 2;8(3):036103. doi: 10.1063/5.0206328. eCollection 2024 Sep.
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Diagnosis and Management of Acute Pancreatitis.急性胰腺炎的诊断与治疗。
Gastroenterology. 2024 Sep;167(4):673-688. doi: 10.1053/j.gastro.2024.02.052. Epub 2024 May 15.
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