Adaikina Alena, Derraik José G B, McMillan Janene, Colle Patricia, Hofman Paul L, Gusso Silmara
Liggins Institute, University of Auckland, Auckland, New Zealand.
Department of Paediatrics: Child and Youth Health, School of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Front Pediatr. 2023 Aug 15;11:1231068. doi: 10.3389/fped.2023.1231068. eCollection 2023.
Previous studies on side-alternating vibration therapy (sVT) have usually used a 9 min intervention protocol. We performed a feasibility study aimed at assessing the safety, acceptability, and potential effectiveness of a longer sVT protocol (15 min per session) in children and adolescents with cerebral palsy (CP).
Fifteen participants aged 5.2-17.4 years (median = 12.4 years) with CP GMFCS level II underwent 20 weeks of sVT consisting of 15 min sessions 4 days/week. Participants were assessed at baseline and after the intervention period, including mobility (six-minute walk-test; 6MWT), body composition (whole-body dual-energy x-ray absorptiometry scans), and muscle function (force plate).
Adherence level to the 15 min VT protocol was 83% on average. There were no adverse events reported. After 20 weeks, there was some evidence for an increase in the walking distance covered in 6MWT (+43 m; = 0.0018) and spine bone mineral density (+0.032 g/cm; = 0.012) compared to baseline.
The 15 min sVT protocol is feasible and well tolerated. The results also suggest potential benefits of this protocol to mobility and bone health. Randomized controlled trials are needed to reliably ascertain the potential effectiveness of a longer sVT protocol on physical function and body composition in young people with CP.
以往关于侧方交替振动疗法（sVT）的研究通常采用9分钟的干预方案。我们进行了一项可行性研究，旨在评估在脑瘫（CP）儿童和青少年中采用更长的sVT方案（每次疗程15分钟）的安全性、可接受性和潜在有效性。
15名年龄在5.2 - 17.4岁（中位数 = 12.4岁）、GMFCS水平为II级的CP患儿接受了为期20周的sVT治疗，每周4天，每次疗程15分钟。在基线期和干预期结束后对参与者进行评估，包括运动能力（6分钟步行试验；6MWT）、身体成分（全身双能X线吸收法扫描）和肌肉功能（测力板）。
对15分钟VT方案的依从性平均为83%。未报告不良事件。20周后，与基线相比，有证据表明6MWT的步行距离有所增加（增加43米；P = 0.0018），脊柱骨密度也有所增加（增加0.032克/立方厘米；P = 0.012）。
15分钟的sVT方案是可行的，且耐受性良好。结果还表明该方案对运动能力和骨骼健康有潜在益处。需要进行随机对照试验来可靠地确定更长的sVT方案对CP青少年身体功能和身体成分的潜在有效性。
