Moody William E, Turvey-Haigh Lauren, Knight Daniel, Coats Caroline J, Cooper Robert M, Schofield Rebecca, Robinson Shaun, Harkness Allan, Oxborough David L, Gillmore Julian D, Whelan Carol, Augustine Daniel X, Fontana Marianna, Steeds Richard P
Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, Birmingham, B15 2TH, UK.
Institute of Cardiovascular Science, College of Medical and Dental Science, University of Birmingham, Birmingham, UK.
Echo Res Pract. 2023 Aug 31;10(1):13. doi: 10.1186/s44156-023-00028-7.
These guidelines form an update of the BSE guideline protocol for the assessment of restrictive cardiomyopathy (Knight et al. in Echo Res Prac, 2013). Since the original recommendations were conceived in 2013, there has been an exponential rise in the diagnosis of cardiac amyloidosis fuelled by increased clinician awareness, improvements in cardiovascular imaging as well as the availability of new and effective disease modifying therapies. The initial diagnosis of cardiac amyloidosis can be challenging and is often not clear-cut on the basis of echocardiography, which for most patients presenting with heart failure symptoms remains the first-line imaging test. The role of a specialist echocardiographer will be to raise the suspicion of cardiac amyloidosis when appropriate, but the formal diagnosis of amyloid sub-type invariably requires further downstream testing. This document seeks to provide a focused review of the literature on echocardiography in cardiac amyloidosis highlighting its important role in the diagnosis, prognosis and screening of at risk individuals, before concluding with a suggested minimum data set, for use as an aide memoire when reporting.
本指南是对评估限制型心肌病的BSE指南协议的更新（Knight等人，《Echo Res Prac》，2013年）。自2013年提出最初建议以来，由于临床医生意识的提高、心血管成像技术的改进以及新型有效疾病修饰疗法的出现，心脏淀粉样变性的诊断呈指数级增长。心脏淀粉样变性的初步诊断可能具有挑战性，基于超声心动图往往并不明确，而对于大多数出现心力衰竭症状的患者，超声心动图仍是一线成像检查。专业超声心动图医生的作用是在适当的时候提高对心脏淀粉样变性的怀疑，但淀粉样蛋白亚型的正式诊断总是需要进一步的下游检测。本文献旨在对心脏淀粉样变性中超声心动图的文献进行重点综述，突出其在诊断、预后及高危个体筛查中的重要作用，最后给出一个建议的最小数据集，用作报告时的辅助记忆。
