Department of Anesthesiology, Ningbo NO. 2 Hospital, Ningbo, China.
Medicine (Baltimore). 2023 Aug 25;102(34):e34736. doi: 10.1097/MD.0000000000034736.
Postoperative nausea and vomiting is a common complication for patients after anesthesia and surgery, which may result in increased parasympathetic activity, such as diaphoresis, pallor, or bradycardia. However, few cases of fatal bradycardia induced by postoperative nausea and vomiting have been reported before. Clinicians generally attribute bradycardia to certain anesthetics, instead of postoperative nausea or vomiting.
A fifty-year-old female with a history of well-controlled hypertension underwent elective radical mastectomy. When recovering from anesthesia in the post-anesthesia care unit, the patient experienced severe bradycardia accompanied by hypotension and unconsciousness, shortly after nausea and vomiting.
The patient received cardiopulmonary resuscitation immediately.
Five minutes later, She recovered sinus rhythm and her vital sings tended to be stable. Three hours later, blood tests showed the N-terminal pro-B-type natriuretic peptide 127 pg/mL and cardiac troponin I 0.44 ng/mL, which peaked to 2.65 ng/mL 10 hours after the emergency. Electrocardiography revealed sinus rhythm, ST-segment depression in the inferior and anterior lateral leads, QTc prolongation, and left ventricular high voltage. Her serum cTnI continued to decline to 0.27 ng/mL on the 3rd day after surgery. She was discharged from the hospital on the fifth day and had no sequelae.
Although postoperative nausea and vomiting occurs frequently, it should be kept in mind as a potential cause to blame for severe bradycardia or even life-threatening situations.
术后恶心和呕吐是患者麻醉和手术后的常见并发症,可导致副交感神经活动增加,如出汗、苍白或心动过缓。然而,以前很少有报道过术后恶心和呕吐引起致命性心动过缓的病例。临床医生通常将心动过缓归因于某些麻醉剂,而不是术后恶心或呕吐。
一位 50 岁女性,有高血压控制良好的病史,择期行根治性乳房切除术。当她在麻醉后恢复室从麻醉中恢复时,患者在经历恶心和呕吐后不久即出现严重心动过缓伴低血压和意识丧失。
患者立即接受心肺复苏。
五分钟后,她恢复窦性心律,生命体征趋于稳定。三小时后,血液检查显示 N 端脑利钠肽前体 127pg/mL 和心肌肌钙蛋白 I 0.44ng/mL,在紧急情况后 10 小时达到 2.65ng/mL 的峰值。心电图显示窦性心律,下壁和前外侧导联 ST 段压低,QTc 延长,左室高电压。她的血清 cTnI 在手术后第 3 天持续下降至 0.27ng/mL。她在第 5 天出院,没有后遗症。
尽管术后恶心和呕吐很常见,但应将其视为潜在的原因,可能导致严重心动过缓甚至危及生命的情况。