Saeed Amir
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, P.O. Box 2440, UAE.
Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Medical Sciences & Technology, Khartoum, Sudan.
Bioinformation. 2022 Oct 31;18(10):938-942. doi: 10.6026/97320630018938. eCollection 2022.
is a well reputed member of Chinese traditional medicine system and is used for managing different ailments since historic times. The present report elucidates the growth impeding effect of R. chingii flower extract against multidrug resistant Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus. The extracts were prepared using standard Soxhlet extraction method using ethanol, methanol and acetone as a solvent. The extracts were further subjected to agar streak method and the stains that showed their sensitivity were further evaluated for minimum inhibitor concentration (MIC) assessment through TCC method. Subsequently the MIC was further used for well diffusion assay. All the strains used in the study showed their sensitivity towards R. chingii flowers extract in respective solvents. Highest antibacterial activity was seen against and whereas the lowest activity was recorded against . Thus the study reported herewith provided an insight into the antibacterial efficacy of R. chingii flower extract against MDR , and .
是中国传统医学体系中久负盛名的一员,自古以来就被用于治疗各种疾病。本报告阐明了青荚叶花提取物对多重耐药性大肠杆菌、肺炎克雷伯菌和金黄色葡萄球菌的生长抑制作用。提取物采用标准索氏提取法制备,以乙醇、甲醇和丙酮为溶剂。提取物进一步采用琼脂划线法,对显示出敏感性的菌株通过TCC法进一步评估最低抑菌浓度(MIC)。随后,MIC进一步用于平板扩散试验。研究中使用的所有菌株在各自溶剂中均对青荚叶花提取物表现出敏感性。对[具体菌株1]和[具体菌株2]观察到最高的抗菌活性,而对[具体菌株3]记录到最低的活性。因此,本研究提供了关于青荚叶花提取物对多重耐药性[具体细菌名称1]、[具体细菌名称2]和[具体细菌名称3]抗菌功效的见解。