Efimova L V
Vopr Med Khim. 1986 Jul-Aug;32(4):41-5.
Dynamics of lipolytic enzymes activity was studied in pre- and postheparin blood plasma of rabbits with hemodynamic heart overloading, with acute local ischemia of myocardium and with diphtheria intoxication. Development of all these pathological processes, impairing myocardium, was accompanied by appearance of lipolytic activity specific for intralipid and for activated intralipid in preheparin blood plasma, by an increase in activity of lipolytic enzymes in postheparin blood plasma as well as by alteration in the spectrum of blood lipoproteins. These alterations depended on the character of disease, impairing the heart muscle.
研究了血流动力学性心脏负荷过重、急性局部心肌缺血和白喉中毒家兔肝素化前后血浆中脂解酶活性的动态变化。所有这些损害心肌的病理过程的发展,均伴有肝素化前血浆中对脂质体和活化脂质体具有特异性的脂解活性的出现、肝素化后血浆中脂解酶活性的增加以及血脂蛋白谱的改变。这些改变取决于损害心肌的疾病性质。