[3-HAA-antigen and immunoreactivity indices in patients with bladder tumors].

Immunologic vigor and 3-hydroxyanthranilic acid (3-HAA)-antigen level were studied in patients with urinary bladder cancer. Leukocyte migration inhibition test demonstrated the inhibitory effect of the said antigen on leukocyte migration in patients with early stage cancer. As tumor advanced, the process accelerated. The 3-HAA-antigen-containing blood serum of bladder cancer patients inhibited the synthesis of rosette-forming cells and antibodies to sheep erythrocytes. A correlation was established between the suppressive effect and tumor stage.