微生物入门：LuxR-LuxI 群体感应。

Microbial Primer: LuxR-LuxI Quorum Sensing.

机构信息

Department of Microbiology, University of Washington School of Medicine, Seattle, WA, USA.

Center for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.

出版信息

Microbiology (Reading). 2023 Sep;169(9). doi: 10.1099/mic.0.001343.

DOI:10.1099/mic.0.001343

PMID:37655474

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10569067/

Abstract

Quorum sensing is a term describing bacterial cell-to-cell communication systems for monitoring and responding to changes in population density. This primer serves as an introduction to the canonical LuxR-LuxI-type quorum sensing circuits common to many species of Gram-negative bacteria. Quorum sensing can synchronize behaviours across a community. Different species employ quorum sensing strategies to control specific behaviours such as bioluminescence, virulence factor production, secondary metabolite production, and biofilm formation.

摘要

群体感应是一个术语，用于描述细菌细胞间的通讯系统，用于监测和响应种群密度的变化。本入门介绍了常见于许多革兰氏阴性菌的典型 LuxR-LuxI 型群体感应回路。群体感应可以使整个群落的行为同步。不同的物种采用群体感应策略来控制特定的行为，如生物发光、毒力因子产生、次生代谢产物产生和生物膜形成。