择期全关节置换术患者金黄色葡萄球菌定植与人工关节周围感染：一项叙述性综述
Staphylococcus aureus colonization and periprosthetic joint infection in patients undergoing elective total joint arthroplasty: a narrative review.
作者信息
de Buys Michael, Moodley Krisantha, Cakic Josip Nenad, Pietrzak Jurek R T
机构信息
Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa.
Emergency Department, ER Consulting, Johannesburg, South Africa.
出版信息
EFORT Open Rev. 2023 Sep 1;8(9):680-689. doi: 10.1530/EOR-23-0031.
Abstract
Peri-prosthetic joint infections (PJIs) following total joint arthroplasty (TJA) are associated with higher treatment costs, longer hospital admissions and increased morbidity and mortality. Colonization with Staphylococcus aureus is an independent and modifiable risk factor for PJIs and carriers of S. aureus are ten times more likely than non-carriers for post-operative infections. Screening and targeted decolonization, vs universal decolonization without screening, remains a controversial topic. We recommend a tailored approach, based on local epidemiological patterns, resource availability and logistical capacity. Universal decolonization is associated with lower rates of SSI and may reduce treatment costs.
摘要
全关节置换术（TJA）后假体周围关节感染（PJI）与更高的治疗成本、更长的住院时间以及发病率和死亡率增加相关。金黄色葡萄球菌定植是PJI的一个独立且可改变的风险因素，金黄色葡萄球菌携带者术后感染的可能性是非携带者的十倍。与不进行筛查的普遍去定植相比，筛查和针对性去定植仍然是一个有争议的话题。我们建议根据当地的流行病学模式、资源可用性和后勤能力采取量身定制的方法。普遍去定植与较低的手术部位感染率相关，并且可能降低治疗成本。
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