Eye Hospital of Shandong First Medical University (Shandong Eye Hospital), Eye Institute of Shandong First Medical University, 372 Jingsi Road, Jinan, 250021, China.
State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Jinan, China.
Lasers Med Sci. 2023 Sep 1;38(1):198. doi: 10.1007/s10103-023-03862-7.
To compare the central corneal thickness (CCT) treated with small incision lenticule extraction (SMILE), femtosecond laser-assisted in situ keratomileusis (FS-LASIK), or laser-assisted subepithelial keratomileusis (LASEK) for myopia correction. This was a retrospective case series study. Patients who had completed 1-year follow-up after receiving SMILE, FS-LASIK, or LASEK at our hospital from January 2019 to July 2021 were included. Pentacam pachymetry was performed to measure the CCT. The predicted CCT reduction was obtained through laser platform. The measured CCT reduction was defined as the difference between the preoperative and postoperative CCT using Pentacam pachymetry. There were 100 eyes treated by SMILE, 100 eyes by FS-LASIK, and 100 eyes by LASEK. There was a significant difference in predicted CCT reduction among the three surgeries (P < 0.001), but no significant difference in measured CCT reduction postoperatively (P = 0.373). At 1 year postoperatively, the CCT reduction was overestimated by 17.85 ± 5.36 µm in the SMILE group, underestimated by 4.31 ± 7.08 µm in the FS-LASIK group, and underestimated by 7.60 ± 8.28 µm in the LASEK group (P < 0.001, P < 0.001). In the FS-LASIK group, the difference between predicted and measured CCT reduction was not related to the predicted CCT reduction (P = 0.095). The laser platform may overestimate the CCT reduction for SMILE and underestimate it for FS-LASIK and LASEK. FS-LASIK has a much higher level of accuracy in CCT reduction, which is not influenced by refractive correction.
比较小切口微透镜提取术（SMILE）、飞秒激光辅助原位角膜磨镶术（FS-LASIK）和激光辅助上皮下角膜磨镶术（LASEK）治疗近视的中央角膜厚度（CCT）。这是一项回顾性病例系列研究。纳入 2019 年 1 月至 2021 年 7 月在我院接受 SMILE、FS-LASIK 或 LASEK 治疗并完成 1 年随访的患者。采用 Pentacam 角膜地形图仪测量 CCT。通过激光平台获得预测 CCT 减少量。使用 Pentacam 角膜地形图仪测量术前和术后 CCT 的减少量，定义为 CCT 减少量。SMILE 组 100 眼，FS-LASIK 组 100 眼，LASEK 组 100 眼。三种手术的预测 CCT 减少量差异有统计学意义（P<0.001），但术后测量 CCT 减少量差异无统计学意义（P=0.373）。术后 1 年，SMILE 组 CCT 减少量高估 17.85±5.36μm，FS-LASIK 组低估 4.31±7.08μm，LASEK 组低估 7.60±8.28μm（P<0.001，P<0.001）。在 FS-LASIK 组，预测 CCT 减少量与测量 CCT 减少量的差异与预测 CCT 减少量无关（P=0.095）。激光平台可能高估 SMILE 的 CCT 减少量，低估 FS-LASIK 和 LASEK 的 CCT 减少量。FS-LASIK 在 CCT 减少方面具有更高的准确性，不受屈光矫正的影响。
