Clinical Medical College of Jining Medical University, Jining, Shandong Province, China.
Department of Radiation Oncology, The First Affiliated Hospital of Shandong First Medical University, Changsha, China.
Medicine (Baltimore). 2023 Sep 1;102(35):e34544. doi: 10.1097/MD.0000000000034544.
Adenoid cystic carcinoma (ACC) of orbit is a very rare epithelial tumor, often originating from the lacrimal glands. At the same time, treatment options are currently limited, such as radiation, chemotherapy. We report a case of a patient treated with antirotinib combined with radiotherapy.
A 13-year-old girl was initially admitted with "left eye swelling for over half a year, 12 days after surgery for left orbital adenoid cystic carcinoma". Initial swelling of the lateral upper eyelid of the left eye, with gradual enlargement and occasional pain.
Left orbital adenoid cystic carcinoma.
After diagnosis of orbital ACC, she underwent resection of the left orbital mass, and received 33 times of adjuvant radiotherapy, but brain metastases appeared later. She refused further treatment, and received 25 times of radiotherapy and anlotinib therapy after the disease progressed again.
Now the patient has been followed up for 8 months, but no progress was found.
Based on this, we hypothesized that radiation therapy in combination with anlotinib is effective for ACC or ACC metastases.
眼眶腺样囊性癌（ACC）是一种非常罕见的上皮性肿瘤，常起源于泪腺。同时，目前的治疗方案有限，如放疗、化疗。我们报告了一例接受安罗替尼联合放疗治疗的患者。
一名 13 岁女孩最初因“左眼肿胀半年以上，左眼腺样囊性癌手术后 12 天”入院。左眼外侧上眼睑肿胀，逐渐增大，偶有疼痛。
左侧眼眶腺样囊性癌。
诊断为眼眶 ACC 后，患者行左眼眶肿块切除术，并接受 33 次辅助放疗，但后来出现脑转移。她拒绝进一步治疗，疾病再次进展后接受 25 次放疗和安罗替尼治疗。
目前患者已随访 8 个月，未见进展。
基于此，我们假设放疗联合安罗替尼对 ACC 或 ACC 转移有效。
