Leisch F, Schützenberger W, Kerschner K, Bergmann H, Maschek W, Dienstl E, Herbinger W
Z Kardiol. 1986 Jul;75(7):426-30.
Percutaneous balloon pulmonary valvuloplasty was performed in 6 adult patients (aged 21-59 years, mean age: 43 years) with congenital pulmonary valve stenosis and systolic pressure gradients of 50 to 120 mm Hg (mean: 78 mm Hg). In 5 patients the procedure was successful: mean systolic right ventricular pressure was reduced from 99 +/- 26 to 55 +/- 7 mm Hg and the trans-stenotic pressure gradient from 77 +/- 28 to 31 +/- 12 mm Hg. Valvuloplasty with a 20 mm balloon was not effective in a patient with a wide pulmonary anulus (diameter 25 mm). In 1 patient only, the balloon occlusion led to severe systemic hypotension with syncope. Short-term follow-up (3 months) demonstrated symptomatic improvement and persistent reduction of the pressure gradient in all successfully treated patients. In conclusion, percutaneous balloon pulmonary valvuloplasty appears to be an effective method with low risk of complications for the treatment of pulmonary valve stenosis in adults.
对6例先天性肺动脉瓣狭窄且收缩压梯度为50至120 mmHg(平均78 mmHg)的成年患者(年龄21 - 59岁,平均年龄43岁)进行了经皮球囊肺动脉瓣成形术。5例患者手术成功:右心室平均收缩压从99±26 mmHg降至55±7 mmHg,跨狭窄压力梯度从77±28 mmHg降至31±12 mmHg。对于1例肺动脉瓣环较宽(直径25 mm)的患者,使用20 mm球囊进行的瓣膜成形术无效。仅1例患者,球囊阻塞导致严重的全身性低血压并伴有晕厥。短期随访(3个月)显示,所有成功治疗的患者症状均有改善,压力梯度持续降低。总之,经皮球囊肺动脉瓣成形术似乎是治疗成人肺动脉瓣狭窄的一种有效方法,并发症风险较低。