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体外冲击波碎石术是目前治疗尿路结石的一线方法吗?

Is extracorporeal lithotripsy a first-line treatment for urinary stones today?

机构信息

Servicio de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid. Spain.

Servicio de Urología, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid. Spain.

出版信息

Actas Urol Esp (Engl Ed). 2024 Mar;48(2):134-139. doi: 10.1016/j.acuroe.2023.08.006. Epub 2023 Aug 30.

DOI:10.1016/j.acuroe.2023.08.006
PMID:37657709
Abstract

OBJECTIVE

To evaluate the efficacy and complications of extracorporeal lithotripsy (SWL) as a first-line treatment for renal and ureteral stones METHODS: Retrospective and observational study of all the patients treated with lithotripsy in a third level center between January 2014 and January 2021; characteristics of the patients, the stones, complications and results of SWL is recollected. Multivariate logistic regression of the factors associated with stone size reduction was performed. A statistical analysis of the factors associated with additional treatment after SWL and factors associated with complications is also executed.

RESULTS

1727 patients are included. Stone mean size was 9,5mm. 1540 (89.4%) patients presented reduction in stone size. In multivariate analysis, stone size (OR=1.13; p=0.00), ureteral location of the lithiasis (OR=1.15; p=0.052) and number of waves (p=0.002; OR=1.00) used in SWL are the factors associated with reduction of stone size. Additional treatment after lithotripsy was needed in 665 patients (38.5%). The factors associated with the need for retreatment were stone size (OR=1.131; p=0.000), number of waves (OR=1.000; p=0.000), energy (OR=1.005; p=0.000). 153 patients (8.8%) suffered complications after SWL. A statistically significant association was found between the size of the lithiasis (p=0.024, OR=1.054) and the previous urinary diversion (P=0.004, OR=0.571).

CONCLUSION

Lithotripsy remains an effective treatment as the first line of therapy for reno-ureteral lithiasis with a low percentage of complications.

摘要

目的

评估体外碎石术(SWL)作为肾和输尿管结石一线治疗的疗效和并发症。

方法

对 2014 年 1 月至 2021 年 1 月期间在三级中心接受碎石术治疗的所有患者进行回顾性和观察性研究;收集患者、结石、并发症的特点以及 SWL 的结果。对与结石大小减小相关的因素进行多变量逻辑回归分析。对 SWL 后附加治疗的相关因素以及并发症的相关因素进行统计学分析。

结果

共纳入 1727 例患者。结石平均大小为 9.5mm。1540(89.4%)例患者结石体积减小。多变量分析显示,结石大小(OR=1.13;p=0.00)、结石位于输尿管的位置(OR=1.15;p=0.052)和 SWL 使用的波数(p=0.002;OR=1.00)是与结石体积减小相关的因素。665 例患者(38.5%)在碎石术后需要进一步治疗。与需要再次治疗相关的因素包括结石大小(OR=1.131;p=0.000)、波数(OR=1.000;p=0.000)、能量(OR=1.005;p=0.000)。SWL 后 153 例(8.8%)患者出现并发症。结石大小(p=0.024,OR=1.054)和先前的尿路改道(P=0.004,OR=0.571)与并发症之间存在统计学显著相关性。

结论

SWL 仍然是一种有效的治疗方法,作为肾输尿管结石的一线治疗方法,其并发症发生率较低。

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