Fischer W, Hegenscheid F, Jende W, Vogler H, Abet L
Zentralbl Gynakol. 1986;108(14):833-40.
An analysis is made in this paper of therapeutic results obtained at Charité Berlin from 14 cases of pure stress incontinence and 6 cases of combined stress-urge incontinence, with reference being made to general benefits and setbacks of transurethral Teflon injection to cope with female urinary incontinence. Five women underwent teflon therapy as the first operation performed on them. Seven women had had one operation before and the rest more than one. Continence was restored in 6 patients (30 per cent), and 3 patients (15 per cent) were improved. The presurgical situation was of minor influence. The definite result was outlined as early as three months from surgery. Urodynamically, Teflon had a favourable impact primarily on functional urethral length and on the stress quotient. However, elevation of the bladder base was radiographically detectable in less numerous cases. Only partial agreement was found to exist between objectivated improvement and subjectively perceived and reported therapeutic results, with falsely positive and falsely negative findings occurring with equal frequency. Micturition was insubstantially impaired by Teflon. However, it should be adopted as a matter of principle that in future teflon should no longer be applied to women for urinary incontinence unless conservative therapy or other surgical incontinence techniques must be skipped for whatever reasons and unless no more effective sphincter substitute is available.
本文分析了柏林夏里特医院对14例单纯性压力性尿失禁和6例混合性压力性-急迫性尿失禁患者的治疗结果，并提及经尿道注射聚四氟乙烯治疗女性尿失禁的总体益处和挫折。5名女性接受聚四氟乙烯治疗作为她们的首次手术。7名女性之前接受过一次手术，其余的接受过不止一次手术。6例患者（30%）恢复了控尿能力，3例患者（15%）病情有所改善。术前情况影响较小。术后三个月即可确定结果。从尿动力学角度看，聚四氟乙烯主要对功能性尿道长度和压力商有有利影响。然而，膀胱底部抬高在较少病例中可通过影像学检测到。客观改善与主观感知和报告的治疗结果之间仅部分一致，假阳性和假阴性结果出现的频率相同。聚四氟乙烯对排尿的影响不大。然而，应遵循一项原则，即除非因任何原因必须跳过保守治疗或其他手术失禁技术，且没有更有效的括约肌替代物，否则未来不应再将聚四氟乙烯应用于女性尿失禁患者。
