School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Chennai 600048, India.
School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Chennai 600048, India; Centre for Surface Technology and Applications, Korea Aerospace University, Goyang 10540, Republic of Korea; Research Centre for Bio Material and Process Development, Incheon National University, Incheon 22012, Republic of Korea.
Int J Biol Macromol. 2023 Dec 31;253(Pt 2):126592. doi: 10.1016/j.ijbiomac.2023.126592. Epub 2023 Aug 31.
Chitosan is a bio-polymer made up of repeating units of N-acetyl glucosamine and glucosamine joined together by (1-4)-glycosidic linkages. Various bioresources have been used to develop bioactive materials that have a wide range of applications in different fields, including industry and medicine. Borassus flabellifer is a well-known source of chitin in the sub-Indian continent and is used in digestion, pharmaceuticals, and other applications. Chitin can be extracted from B. flabellifer fruit shells through demineralization and deproteinization and then converted into chitosan through deacetylation. This study aimed to investigate the biological activity of chitosan extracted from B. flabellifer fruit shells and to analyze its molecular structure using FT-IR analysis. Results showed the presence of NH, OH, and CO stretching, indicating the presence of various functional groups in chitosan. Scanning electron microscopic study revealed the topography of the chitosan. Well-diffusion and MIC tests showed that chitosan exhibited activity against E. coli and S. aureus. The chitosan extract also exhibited potential antioxidant polymer by scavenging free radicals.
壳聚糖是一种由 N-乙酰葡萄糖胺和葡萄糖胺重复单元通过（1-4）-糖苷键连接而成的生物聚合物。各种生物资源已被用于开发具有广泛应用领域的生物活性材料，包括工业和医学。砂糖椰子是印度次大陆地区一种广为人知的甲壳素来源，用于消化、制药和其他应用。壳聚糖可以通过脱矿质和脱蛋白作用从砂糖椰子果实壳中提取出来，然后通过脱乙酰作用转化为壳聚糖。本研究旨在研究从砂糖椰子果实壳中提取的壳聚糖的生物活性，并通过傅里叶变换红外（FT-IR）分析对其分子结构进行分析。结果表明壳聚糖中存在 NH、OH 和 CO 伸缩振动，表明壳聚糖中存在各种功能基团。扫描电子显微镜研究揭示了壳聚糖的形貌。良好的扩散和 MIC 试验表明壳聚糖对大肠杆菌和金黄色葡萄球菌具有活性。壳聚糖提取物还通过清除自由基表现出潜在的抗氧化聚合物。
