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[有或无声音暴露的实验性动脉粥样硬化中大脑皮质结构的变化]

[Changes in the structures of the cerebral cortex in experimental atherosclerosis with and without exposure to sound].

作者信息

Iakhin F A, Popova E N, Krivitskaia G N, Bazaz'ian G G

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(7):1066-70.

PMID:3765995
Abstract

Albino rats fed an atherogenic diet for 3 months developed a marked depression of the anti-coagulation system of blood. The acoustic and sensomotor cortex showed dystrophic changes in the cortical structures, as well as signs of the reparative nature. Sound stimulation in the presence of atherosclerosis increased fibrinolytic activity and decreased heparin tolerance of blood plasma in animals sensitive to acoustic exposure and led to a greater severity and dissemination of dystrophic and destructive changes in the cortical structures, particularly in animals with convulsive seizures.

摘要

喂食致动脉粥样化饮食3个月的白化大鼠出现了血液抗凝系统的显著抑制。听觉和感觉运动皮层的皮质结构出现了营养不良性变化以及修复性迹象。在动脉粥样硬化存在的情况下,声音刺激会增加对声音暴露敏感的动物的纤溶活性,降低血浆的肝素耐受性,并导致皮质结构中营养不良性和破坏性变化更加严重且扩散,尤其是在有惊厥发作的动物中。

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