COUCH Health, 5 Richmond St, Manchester M1 3HF, UK
Centre for Rural Health, University of Aberdeen, Centre for Health Science, Old Perth Road, Inverness, IV2 3JH, UK
Rural Remote Health. 2023 Sep;23(3):7793. doi: 10.22605/RRH7793. Epub 2023 Sep 3.
People living rurally face health inequities fuelled by social exclusion, access to and awareness of health services, and poor transport links. In order to improve the acceptability, accessibility and applicability of health and care interventions, it is important that clinical trial participant populations include people living rurally. Identifying strategies that improve recruitment of rural participants to trials will support trialists, reduce research waste and contribute to alleviating health inequalities experienced by rural patients. The objective of the review is to quantify the effects of randomised evaluations of strategies to recruit rural participants to randomised controlled trials.
The following databases will be searched for relevant studies: Ovid MEDLINE, Embase, Cochrane Library, Web of Science All, EBSCO CINAHL, Proquest, ERIC, IngentaConnect, Web of Science SSCI and AHCI, and Scopus. Any randomised evaluation of a recruitment intervention aiming to improve recruitment of rural participants to a randomised trial will be included. We will not apply any restriction on publication date, language or journal. The primary, and only, outcome of our review will be the proportion of participants recruited to a randomised controlled trial. Two reviewers will independently screen abstracts and titles for eligible studies, and then full texts of relevant records will be reviewed by the same two reviewers. Where disagreements cannot be resolved through discussion, a third reviewer will adjudicate.
We will assess the methodological quality of individual studies using the Cochrane risk of bias tool, and the GRADE approach will be applied to determine the certainty of the evidence within each comparison.
This systematic review will quantify the effects of randomised evaluations of strategies to recruit rural participants to trials. Our findings will contribute to the evidence base to support trial teams to recruit a participant population that represents society as a whole, informing future research and playing a part to alleviate health inequalities between rural and urban populations.
由于社会排斥、获取和了解卫生服务的机会以及交通联系不畅，农村居民面临着健康不平等的问题。为了提高卫生和保健干预措施的可接受性、可及性和适用性，临床试验参与者人群中包括农村居民非常重要。确定可提高农村参与者参与试验的招募策略，将有助于试验人员减少研究浪费，并有助于缓解农村患者所经历的健康不平等问题。本研究的目的是定量评估随机评价招募农村参与者参与随机对照试验的策略的效果。
将对以下数据库进行搜索，以查找相关研究：Ovid MEDLINE、Embase、Cochrane 图书馆、Web of Science 所有、EBSCO CINAHL、Proquest、ERIC、IngentaConnect、Web of Science SSCI 和 AHCI 以及 Scopus。将纳入旨在提高农村参与者参与随机试验招募的任何随机评估招募干预措施的研究。我们不会对发表日期、语言或期刊进行任何限制。本综述的主要（也是唯一）结果将是参与随机对照试验的参与者比例。两名审查员将独立筛选摘要和标题以确定符合条件的研究，然后由同两名审查员审查相关记录的全文。如果无法通过讨论解决分歧，则由第三名审查员进行裁决。
我们将使用 Cochrane 偏倚风险工具评估个体研究的方法学质量，并应用 GRADE 方法确定每个比较中证据的确定性。
本系统评价将定量评估随机评价招募农村参与者参与试验的策略的效果。我们的研究结果将为支持招募代表整个社会的参与者人群的试验团队提供证据基础，为未来的研究提供信息，并为缓解农村和城市人口之间的健康不平等做出贡献。
