Saugbjerg P, Asoh T, Lund C, Kühl V, Kehlet H
Acta Anaesthesiol Scand. 1986 Jul;30(5):400-3. doi: 10.1111/j.1399-6576.1986.tb02438.x.
The effect of epidural analgesia with plain bupivacaine 0.5% on somatosensory evoked potentials (SEP) to electrical stimulation of the posterior tibial nerve was examined in six patients. Epidural analgesia significantly increased onset time and latencies of the early components in SEP, while the amplitudes decreased. These results suggest that SEP may be valuable in the objective evaluation of possible differential neural effects of local anaesthetic agents following epidural or intrathecal administration.
对6例患者研究了0.5% 布比卡因单纯溶液硬膜外镇痛对胫后神经电刺激体感诱发电位（SEP）的影响。硬膜外镇痛显著延长了SEP早期成分的起始时间和潜伏期，同时波幅降低。这些结果提示，SEP可能有助于客观评估硬膜外或鞘内给药后局部麻醉药可能产生的不同神经效应。
