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一例伴有再生障碍性贫血的类圆线虫病:一种表现罕见的常见疾病。

A case of strongyloidiasis with aplastic anaemia: A common disease with an uncommon presentation.

作者信息

Singh Alka, Prasad Pallavi, Singh Anurag

机构信息

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

出版信息

IDCases. 2023 Aug 24;33:e01883. doi: 10.1016/j.idcr.2023.e01883. eCollection 2023.

Abstract

Strongyloidiasis is an opportunistic infection caused by the nematode helminth and transmitted mostly via soil. The disease is usually asymptomatic, limited, and long-standing. Herein, we report a case of strongyloidiasis in a patient who seemed to be immunocompetent despite his malnourished appearance. He was presented with pancytopenia and aplastic anaemia and well responded to albendazole therapy with complete resolution of symptoms within three months. We recommend, prior to beginning of immunosuppressive regimens, it may be prudent to examine all patients presenting with abdominal discomfort along with pancytopenia for a possible worm infestation. Bone marrow suppression induced by worm infestation is an extremely rare but potentially comorbid condition that can lead to pancytopenia and severe aplastic anaemia.

摘要

类圆线虫病是一种由线虫蠕虫引起的机会性感染,主要通过土壤传播。该病通常无症状、病程有限且持续时间长。在此,我们报告一例类圆线虫病病例,该患者尽管外表营养不良,但似乎免疫功能正常。他出现了全血细胞减少和再生障碍性贫血,对阿苯达唑治疗反应良好,症状在三个月内完全缓解。我们建议,在开始免疫抑制治疗方案之前,对所有出现腹部不适并伴有全血细胞减少的患者进行检查,以排查可能的蠕虫感染,这可能是谨慎之举。蠕虫感染引起的骨髓抑制是一种极其罕见但可能并存的情况,可导致全血细胞减少和严重再生障碍性贫血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c614/10474063/e4762c59cf66/gr1.jpg

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