Kumar Lakshya, Kachhadia Meet Popatbhai, Kaur Jashanpreet, Patel Harshkumar, Noor Khutaija, Gohel Rushi G, Kaur Paramjeet, Raiyani Siddharth, Gohel Vatsal A, Vasavada Advait M
Internal Medicine, Pandit Dindayal Upadhyay (PDU) Medical College, Rajkot, IND.
Internal Medicine, Mata Gujri Memorial Medical College, Kishanganj, IND.
Cureus. 2023 Jul 31;15(7):e42772. doi: 10.7759/cureus.42772. eCollection 2023 Jul.
Myasthenia gravis (MG) is an autoimmune disease affecting young women in their second and third decades, coinciding with their reproductive years. We aim to explore the choices and challenges in the treatment of MG in pregnancy. Cochrane, PubMed, Google Scholar, and Embase were the four databases systematically searched for studies with patients reporting pregnancy outcomes for women with MG during pregnancy using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) technique. Quality assessment was done using the Joanna Briggs Institute critical tool (JBI, Adelaide, Australia) for methodological quality. From 2000 to 2023, 40 studies from database search results were considered. There is a substantial risk of complications with MG, especially if it appears during pregnancy. In particular, widespread weakness is a cause of severe, life-threatening disorders, but several treatment options are available.
重症肌无力（MG）是一种自身免疫性疾病，好发于二三十岁的年轻女性，这与她们的育龄期相吻合。我们旨在探讨妊娠合并重症肌无力治疗中的选择与挑战。通过Cochrane、PubMed、谷歌学术和Embase这四个数据库，运用系统评价和Meta分析的首选报告项目（PRISMA）技术，系统检索了有关报告重症肌无力女性患者妊娠结局的研究。使用乔安娜·布里格斯研究所关键工具（澳大利亚阿德莱德的JBI）对方法学质量进行了评估。从2000年到2023年，共纳入了数据库搜索结果中的40项研究。重症肌无力有发生并发症的重大风险，尤其是在孕期发病时。特别是广泛肌无力是导致严重的、危及生命疾病的原因，但有几种治疗选择可供使用。
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