Kühnert Maritta, Schmidt Markus, Kuschel Bettina, Schäfer-Graf Ute Margaretha
Obstetrics, UFK Marburg, Marburg, Germany.
Gynecology & Obstetrics, Sana Kliniken Duisburg GmbH, Duisburg, Germany.
Geburtshilfe Frauenheilkd. 2021 Dec 8;81(12):1301-1306. doi: 10.1055/a-1541-7964. eCollection 2021 Dec.
Myasthenia gravis is an autoimmune disease with a range of clinical presentations which manifest as combinations of weakness of the ocular, bulbar, and respiratory muscle groups and muscles of the extremities. Young women of reproductive age are most commonly affected. Preconception planning, the impact of pregnancy, prepartum management, drug therapy in pregnancy, myasthenic and cholinergic crises, fetal monitoring, peripartum management including analgesia and anesthesia during labor and cesarean section as well as neonatal management and neonatal myasthenia gravis are described here and the appropriate recommendations are given.
重症肌无力是一种自身免疫性疾病,有一系列临床表现,表现为眼肌、延髓肌、呼吸肌群和四肢肌肉无力的组合。育龄期年轻女性最常受累。本文描述了孕前规划、妊娠的影响、产前管理、孕期药物治疗、肌无力和胆碱能危象、胎儿监测、围产期管理(包括分娩和剖宫产期间的镇痛和麻醉)以及新生儿管理和新生儿重症肌无力,并给出了适当的建议。