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荔枝壳孢属软组织感染：病例报告及治疗考量

Lecythophora Soft-Tissue Infection: Case Report and Treatment Considerations.

作者信息

Golden Ryan, Quimby David S

机构信息

Infectious Diseases, CommonSpirit Health, Omaha, USA.

Medicine/Infectious Diseases, Creighton University, Omaha, USA.

出版信息

Cureus. 2023 Aug 3;15(8):e42919. doi: 10.7759/cureus.42919. eCollection 2023 Aug.

DOI:10.7759/cureus.42919
PMID:37664280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10474948/
Abstract

is a saprophytic fungus commonly found in the environment. Able to be isolated from soil, it is frequently associated with the soft rot of wood. Although human infections are not common, they have been reported, and have ranged from keratitis and soft-tissue infection to deep osteomyelitis and endometritis. Here we report a case of soft-tissue infection with this pathogen along with successful treatment with standard-dose terbinafine when other agents were unavailable. The true prevalence of infections with this pathogen is unclear and further data are needed to determine optimal therapy.

摘要

是一种常见于环境中的腐生真菌。它能够从土壤中分离出来，经常与木材的软腐病有关。虽然人类感染并不常见，但已有报道，感染范围从角膜炎和软组织感染到深部骨髓炎和子宫内膜炎。在此，我们报告一例由该病原体引起的软组织感染病例，以及在无法使用其他药物时使用标准剂量特比萘芬成功治疗的情况。这种病原体感染的真实患病率尚不清楚，需要更多数据来确定最佳治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/a2f21e74ae87/cureus-0015-00000042919-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/0f031f5f88c7/cureus-0015-00000042919-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/645a08930448/cureus-0015-00000042919-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/2343e338a5f5/cureus-0015-00000042919-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/bfbe47c34a30/cureus-0015-00000042919-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/a2f21e74ae87/cureus-0015-00000042919-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/0f031f5f88c7/cureus-0015-00000042919-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/645a08930448/cureus-0015-00000042919-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/2343e338a5f5/cureus-0015-00000042919-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/bfbe47c34a30/cureus-0015-00000042919-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce7a/10474948/a2f21e74ae87/cureus-0015-00000042919-i05.jpg

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本文引用的文献

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First Reported Case of Invasive Cutaneous Infection in a Patient With Acute Myelogenous Leukemia: A Case Report and Literature Review.急性髓系白血病患者侵袭性皮肤感染首例报告：病例报告及文献复习
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Answer to March 2020 Photo Quiz.2020年3月照片测验答案。
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J Clin Microbiol. 2020 Feb 24;58(3). doi: 10.1128/JCM.01862-18.
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Identification and Antifungal Susceptibility of Penicillium-Like Fungi from Clinical Samples in the United States.美国临床样本中类青霉属真菌的鉴定及抗真菌药敏性
J Clin Microbiol. 2016 Aug;54(8):2155-61. doi: 10.1128/JCM.00960-16. Epub 2016 Jun 8.
5
Terbinafine in combination with other antifungal agents for treatment of resistant or refractory mycoses: investigating optimal dosing regimens using a physiologically based pharmacokinetic model.特比萘芬联合其他抗真菌药物治疗耐药或难治性真菌感染：应用生理基于药代动力学模型探索最佳给药方案。
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Coniochaeta polymorpha, a new species from endotracheal aspirate of a preterm neonate, and transfer of Lecythophora species to Coniochaeta.多形外瓶霉，来自早产儿气管内吸引物的一个新种，以及将 Lecythophora 种转移到 Coniochaeta 属。
Antonie Van Leeuwenhoek. 2013 Aug;104(2):243-52. doi: 10.1007/s10482-013-9943-z. Epub 2013 Jun 9.
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Molecular and phenotypic characterization of Phialemonium and Lecythophora isolates from clinical samples.从临床样本中分离的 Phialemonium 和 Lecythophora 的分子和表型特征。
J Clin Microbiol. 2011 Apr;49(4):1209-16. doi: 10.1128/JCM.01979-10. Epub 2011 Jan 26.
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Lecythophora hoffmannii isolated from a case of canine osteomyelitis in Japan.从日本一例犬骨髓炎病例中分离出的霍夫曼梨孢菌。
Med Mycol. 2007 May;45(3):267-72. doi: 10.1080/13693780601188602.
9
Deep-seated trichosporonosis in an immunocompetent patient: a case report of uterine trichosporonosis-correction.免疫功能正常患者的深部毛孢子菌病：一例子宫毛孢子菌病修正的病例报告
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