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一名接受持续性非卧床腹膜透析(CAPD)治疗的患者,尽管接受了看似足够的全身性和腹腔内两性霉素B治疗,但念珠菌仍持续存在。

Persistence of Candida despite seemingly adequate systemic and intraperitoneal amphotericin B treatment in a patient on CAPD.

作者信息

Bastani B, Westervelt F B

出版信息

Am J Kidney Dis. 1986 Oct;8(4):265-6. doi: 10.1016/s0272-6386(86)80038-5.

Abstract

A case of Candida peritonitis in a patient on continuous ambulatory peritoneal dialysis (CAPD) is presented. Despite 2 weeks of intravenous and 4 weeks of intraperitoneal amphotericin B, good clinical response, and repeatedly negative fungal cultures from the peritoneal dialysate, her Tenckhoff catheter upon removal grew the same Candida species. This case emphasizes the point that Candida may persist on the catheter despite seemingly adequate antifungal treatment and good clinical and microbiologic response.

摘要

本文报告一例持续性非卧床腹膜透析(CAPD)患者发生念珠菌性腹膜炎的病例。尽管给予了2周的静脉注射两性霉素B和4周的腹腔内注射两性霉素B,患者临床反应良好,腹膜透析液真菌培养多次呈阴性,但拔除的Tenckhoff导管培养出了相同的念珠菌菌种。该病例强调了一点,即尽管抗真菌治疗看似充分,临床和微生物学反应良好,但念珠菌仍可能在导管上持续存在。

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