Struijk D G, Krediet R T, Boeschoten E W, Rietra P J, Arisz L
Am J Kidney Dis. 1987 Jan;9(1):66-70. doi: 10.1016/s0272-6386(87)80164-6.
Nine peritonitis episodes caused by Candida sp were diagnosed in eight continuous ambulatory peritoneal dialysis (CAPD) patients. Treatment with intraperitoneal administration of amphotericin B and 5-fluorocytosine while the peritoneal catheter was left in situ was effective in six episodes in five patients. Of the three other patients, two started again with CAPD after peritonitis had been cured, but one patient preferred to stay on hemodialysis. In four episodes, peritoneal white cell counts remained high during treatment despite negative cultures. This was probably the result of irritation of the peritoneal membrane caused by the antifungal treatment, possibly by amphotericin B. Persistently-elevated leukocyte counts during antifungal therapy, with or without signs and symptoms of peritonitis, are not necessarily an indication of treatment failure.
在8例持续性非卧床腹膜透析（CAPD）患者中诊断出9次念珠菌属引起的腹膜炎发作。在5例患者的6次发作中，在保留腹膜导管原位的情况下腹腔内给予两性霉素B和5-氟胞嘧啶治疗有效。另外3例患者中，2例在腹膜炎治愈后再次开始CAPD，但1例患者更倾向于继续进行血液透析。在4次发作中，尽管培养结果为阴性，但治疗期间腹膜白细胞计数仍居高不下。这可能是抗真菌治疗（可能是两性霉素B）刺激腹膜所致。抗真菌治疗期间白细胞计数持续升高，无论有无腹膜炎的体征和症状，不一定表明治疗失败。
