He Long, Zhu Jinhan, Wang Xuetao, Zhang Bailin, Hu Qiang, Chen Lixin, Liu Xiaowei
School of Physics, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University Cancer Center, Guangzhou, China.
J Appl Clin Med Phys. 2023 Oct;24(10):e14138. doi: 10.1002/acm2.14138. Epub 2023 Sep 4.
To develop a novel ionization chamber array dosimetry system, study its dosimetry characteristics, and perform preliminary tests for plan dose verification.
The dosimetry characteristics of this new array were tested, including short-term and long-term reproducibility, dose linearity, dose rate dependence, field size dependence, and angular dependence. The open field and MLC field plans were designed for dose testing. Randomly select 30 patient treatment plans (10 intensity-modulated radiation therapy [IMRT] plans and 20 volumetric modulated arc therapy [VMAT] plans) that have undergone dose verification using Portal Dosimetry to perform verification measurement and evaluate dose verification test results.
The dosimetry characteristics of the arrays all performed well. The gamma passing rates (3%/2 mm) were more than 96% for the combined open field and MLC field plans. The average gamma pass rates were (99.54 ± 0.58)% and (96.70 ± 3.41)% for the 10 IMRT plans and (99.32 ± 0.89)% and (94.91 ± 6.01)% for the 20 VMAT plans at the 3%/2 mm and 2%/2 mm criteria, respectively, which is similar to the Portal Dosimetry's measurement results.
This novel ionization chamber array demonstrates good dosimetry characteristics and is suitable for clinical IMRT and VMAT plan verifications.
开发一种新型电离室阵列剂量测定系统，研究其剂量测定特性，并进行计划剂量验证的初步测试。
测试了这种新阵列的剂量测定特性，包括短期和长期重复性、剂量线性、剂量率依赖性、射野大小依赖性和角度依赖性。设计了开放射野和多叶准直器（MLC）射野计划用于剂量测试。随机选择30个已使用门静脉剂量测定法进行剂量验证的患者治疗计划（10个调强放射治疗[IMRT]计划和20个容积调强弧形治疗[VMAT]计划）进行验证测量，并评估剂量验证测试结果。
阵列的剂量测定特性均表现良好。开放射野和MLC射野联合计划的γ通过率（3%/2毫米）超过96%。在3%/2毫米和2%/2毫米标准下，10个IMRT计划的平均γ通过率分别为（99.54±0.58）%和（96.70±3.41）%，20个VMAT计划的平均γ通过率分别为（99.32±0.89）%和（94.91±6.01）%，与门静脉剂量测定法的测量结果相似。
这种新型电离室阵列显示出良好的剂量测定特性，适用于临床IMRT和VMAT计划验证。
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