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基因组学与奶牛繁殖力

Genomics and Dairy Bull Fertility.

作者信息

Peñagaricano Francisco

机构信息

Department of Animal and Dairy Sciences, University of Wisconsin-Madison.

出版信息

Vet Clin North Am Food Anim Pract. 2024 Mar;40(1):185-190. doi: 10.1016/j.cvfa.2023.08.005. Epub 2023 Sep 4.

Abstract

Current evidence suggests that dairy bull fertility is influenced by genetic factors, and hence, it could be managed and improved by genetic means. There are major mutations that explain about 4% to 8% of the observed differences in conception rate between bulls segregating in most dairy breeds. Research has shown that genomic prediction of bull fertility is possible, and this could be used to make accurate genome-guided selection decisions, such as early culling of predicted subfertile bull calves. Inbreeding negatively influences bull fertility, and the increase in homozygosity seems an important risk factor for dairy bull subfertility.

摘要

目前的证据表明,奶牛公牛的繁殖力受遗传因素影响,因此,可以通过遗传手段进行管理和提高。在大多数奶牛品种中,有一些主要突变可解释公牛之间观察到的受孕率差异的4%至8%。研究表明,对公牛繁殖力进行基因组预测是可行的,这可用于做出准确的基因组指导选择决策,如早期淘汰预测为繁殖力低下的公牛犊。近亲繁殖对公牛繁殖力有负面影响,纯合性增加似乎是奶牛公牛繁殖力低下的一个重要风险因素。

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