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不同分期系统在神经母细胞瘤中的预后价值及肿瘤切除的完整性

Prognostic value of different staging systems in neuroblastomas and completeness of tumour excision.

作者信息

Carlsen N L, Christensen I J, Schroeder H, Bro P V, Hesselbjerg U, Jensen K B, Nielsen O H

出版信息

Arch Dis Child. 1986 Sep;61(9):832-42. doi: 10.1136/adc.61.9.832.

Abstract

Two hundred and fifty three patients were retrospectively assigned to eight different staging systems proposed for neuroblastomas, and the prognostic value of each staging system was evaluated individually. The ability of each system to predict prognosis was compared with the others and the system proposed by Evans et al found to be the best predictor, even better than the recently proposed Tumour-Nodes-Metastases staging system. This is probably due to the fact that factors other than the resectability of the tumour play a major role in the survival of these children. Age was found to have independent prognostic significance whatever staging system was used.

摘要

253名患者被回顾性地归入为神经母细胞瘤提出的8种不同分期系统,并且分别评估了每种分期系统的预后价值。将每个系统预测预后的能力与其他系统进行比较,发现Evans等人提出的系统是最好的预测指标,甚至优于最近提出的肿瘤-淋巴结-转移分期系统。这可能是因为除肿瘤可切除性之外的因素在这些儿童的生存中起主要作用。无论使用何种分期系统,年龄都被发现具有独立的预后意义。

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本文引用的文献

5
Surgicopathologic staging of neuroblastoma: prognostic significance of regional lymph node metastases.
J Pediatr. 1983 Jan;102(1):59-62. doi: 10.1016/s0022-3476(83)80287-x.
6
Prognostic factors in neuroblastomas.
Acta Pathol Microbiol Immunol Scand A. 1983 Sep;91(5):365-71. doi: 10.1111/j.1699-0463.1983.tb02767.x.
8
Proposed classification of neuroblastoma.神经母细胞瘤的拟议分类。
J Pediatr. 1967 Nov;71(5):764. doi: 10.1016/s0022-3476(67)80219-1.
9
Survival of children with neuroblastoma treated with combination chemotherapy.
J Pediatr. 1968 Dec;73(6):928-31. doi: 10.1016/s0022-3476(68)80252-5.
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Observations on the histopathology of neuroblastomas.神经母细胞瘤的组织病理学观察
J Pediatr Surg. 1968 Feb;3(1):106-10. doi: 10.1016/0022-3468(68)90989-5.

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