Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
J Cell Biol. 2023 Oct 2;222(10). doi: 10.1083/jcb.202308028. Epub 2023 Sep 7.
Mechanosensory neurons utilize specialized compartments called mechanosensory organelles (MOs) to process external forces, yet the MO organization mechanisms remained unclear. In this issue, Song et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202209116) discovered that a microtubule-binding protein, DCX-EMAP, is the key organizer of fly MOs.
机械感觉神经元利用称为机械感觉细胞器 (MOs) 的专门隔室来处理外力,但 MO 的组织机制仍不清楚。在本期杂志中,Song 等人(2023. J. Cell Biol.https://doi.org/10.1083/jcb.202209116)发现,微管结合蛋白 DCX-EMAP 是果蝇 MO 的关键组织者。