抵抗是徒劳的：集中力产生用于不对称细胞分裂。
Resistance is futile: Centering forces yield for asymmetric cell division.
机构信息
Department of Physics and Astronomy and Department of Biological Sciences, Eukaryotic Pathogen Innovation Center Faculty Scholar, Clemson University, Clemson, SC
Departments of Cell and Developmental Biology, Chemical and Biomolecular Engineering, and Biochemistry, Vanderbilt University, Nashville, TN
出版信息
J Cell Biol. 2019 Mar 4;218(3):727-728. doi: 10.1083/jcb.201902039. Epub 2019 Feb 15.
Asymmetric cell division relies on microtubule-based forces to asymmetrically position the mitotic apparatus. In this issue, Sallé et al. (2019. https://doi.org/10.1083/jcb.201807102) use magnetic tweezers to induce asymmetric division in sea urchin zygotes, demonstrating that asymmetry could arise from a time-dependent weakening of centering forces.
不对称细胞分裂依赖于基于微管的力来将有丝分裂装置不对称定位。在本期中，Sallé 等人（2019. https://doi.org/10.1083/jcb.201807102）使用磁镊在海胆受精卵中诱导不对称分裂，证明不对称性可能源于中心体定位力的时间依赖性减弱。
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