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运动想象脑机接口在脑卒中后上肢运动功能障碍康复中的应用

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke.

作者信息

Jiang Yongchun, Yin Junxiao, Zhao Biyi, Zhang Yajie, Peng Tingting, Zhuang Wanqi, Wang Siqing, Huang Siqi, Zhong Meilian, Zhang Yanni, Tang Guibing, Shen Bingchi, Ou Haining, Zheng Yuxin, Lin Qiang

机构信息

Guangzhou Medical University; Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University; Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University.

Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine.

出版信息

J Vis Exp. 2023 Sep 1(199). doi: 10.3791/65405.

DOI:10.3791/65405
PMID:37677045
Abstract

The rehabilitation effect of patients with moderate or severe upper limb motor dysfunction after stroke is poor, which has been the focus of research owing to the difficulties encountered. Brain-computer interface (BCI) represents a hot frontier technology in brain neuroscience research. It refers to the direct conversion of the sensory perception, imagery, cognition, and thinking of users or subjects into actions, without reliance on peripheral nerves or muscles, to establish direct communication and control channels between the brain and external devices. Motor imagery brain-computer interface (MI-BCI) is the most common clinical application of rehabilitation as a non-invasive means of rehabilitation. Previous clinical studies have confirmed that MI-BCI positively improves motor dysfunction in patients after stroke. However, there is a lack of clinical operation demonstration. To that end, this study describes in detail the treatment of MI-BCI for patients with moderate and severe upper limb dysfunction after stroke and shows the intervention effect of MI-BCI through clinical function evaluation and brain function evaluation results, thereby providing ideas and references for clinical rehabilitation application and mechanism research.

摘要

中风后中重度上肢运动功能障碍患者的康复效果较差,由于面临诸多困难,这一直是研究的重点。脑机接口(BCI)是脑神经科学研究中的一项前沿热门技术。它是指将用户或受试者的感觉、想象、认知和思维直接转化为行动,无需依赖外周神经或肌肉,从而在大脑与外部设备之间建立直接的通信和控制通道。运动想象脑机接口(MI-BCI)作为一种非侵入性康复手段,是最常见的临床康复应用。以往的临床研究证实,MI-BCI能积极改善中风后患者的运动功能障碍。然而,缺乏临床操作示范。为此,本研究详细描述了MI-BCI对中风后中重度上肢功能障碍患者的治疗情况,并通过临床功能评估和脑功能评估结果展示了MI-BCI的干预效果,从而为临床康复应用和机制研究提供思路和参考。

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引用本文的文献

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Effects of dual-task mode brain-computer interface based on motor imagery and virtual reality on balance and attention in patients with stroke: a randomized controlled pilot trial.基于运动想象和虚拟现实的双任务模式脑机接口对中风患者平衡和注意力的影响:一项随机对照试验。
J Neuroeng Rehabil. 2025 Aug 29;22(1):187. doi: 10.1186/s12984-025-01730-9.
2
Motor imagery-based brain-computer interface rehabilitation programs enhance upper extremity performance and cortical activation in stroke patients.基于运动想象的脑-机接口康复方案可改善脑卒中患者的上肢功能和皮层激活。
J Neuroeng Rehabil. 2024 May 29;21(1):91. doi: 10.1186/s12984-024-01387-w.