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[重庆居民膳食铅暴露的概率风险评估]

[Probabilistic risk assessment of dietary exposure to lead among Chongqing residents].

作者信息

Chen Jiahui, Chen Jingrong, Feng Ping, Long Cheng, Wu Ailin, Zou Qinpei, Luo Shuquan, Zhao Jian, Zhang Huadong, Lian Xuemei, Huo Jiao

机构信息

Chongqing Center for Disease Control and Prevention, Chongqing 400042, China.

School of Public Health, Chongqing Medical University, Chongqing 400016, China.

出版信息

Wei Sheng Yan Jiu. 2023 Jul;52(4):611-617. doi: 10.19813/j.cnki.weishengyanjiu.2023.04.015.

Abstract

OBJECTIVE

To investigate lead contamination in commercial foods in Chongqing City, and to assess the health risk of dietary lead exposure of residents in Chongqing City.

METHODS

Lead concentration data was obtained from the food safety risk monitoring system, which included a total of 2347 lead-containing food samples in 11 categories in Chongqing from 2016 to 2020. Consumption data was derived from the China Health and Nutrition Survey Project in Chongqing in 2018(3 day, 24 h dietary recall survey). The dietary exposure to lead of residents in Chongqing was calculated by the Monte Carlo simulation method and the margin of exposure(MOE) method was used to evaluate the health risk of the population.

RESULTS

The average content of lead in 2347 food samples from 11 categories ranged from 0.0328 to 0.0363 mg/kg, with an overall detection rate of 58.5%. For people aged between 3-6, 7-17, 18-59, and ≥ 60 years, the mean dietary lead intakes in Chongqing were 0.935-1.070, 0.600-0.684, 0.367-0.416, 0.369-0.419 μg/(kg·BW·d), respectively; and the high levels of dietary lead exposure(P95) were 1.642-1.852, 1.147-1.299, 0.651-0.729, 0.659-0.740 μg/(kg·BW·d), respectively. MOE values for lead were less than 1 for age groups 3-6 and 7-17 years. Mean MOE values for lead were greater than 1 for ages 18 to 59 and ≥ 60. Cereals and their products, vegetables and their products, and meat and meat products were the main sources of dietary lead exposure, accounting for more than 85% of the total dietary lead exposure.

CONCLUSION

There are potential health risks of lead for residents in Chongqing.

摘要

目的

调查重庆市市售食品中的铅污染情况,并评估重庆市居民膳食铅暴露的健康风险。

方法

从食品安全风险监测系统获取铅浓度数据,该数据涵盖2016年至2020年重庆市11类共2347份含铅食品样本。消费数据来自2018年中国健康与营养调查重庆项目(3天24小时膳食回顾调查)。采用蒙特卡洛模拟法计算重庆市居民膳食铅暴露量,并使用暴露边际(MOE)法评估人群的健康风险。

结果

11类2347份食品样本中铅的平均含量在0.0328至0.0363毫克/千克之间,总体检出率为58.5%。对于3至6岁、7至17岁、18至59岁和≥60岁人群,重庆市膳食铅平均摄入量分别为0.935至1.070、0.600至0.684、0.367至0.416、0.369至0.419微克/(千克体重·天);膳食铅暴露高水平(P95)分别为1.642至1.852、1.147至1.299、0.651至0.729、0.659至0.740微克/(千克体重·天)。3至6岁和7至17岁年龄组铅的MOE值小于1。18至59岁和≥60岁年龄组铅的平均MOE值大于1。谷类及其制品、蔬菜及其制品、肉类及其制品是膳食铅暴露的主要来源,占膳食铅总暴露量的85%以上。

结论

重庆市居民存在铅的潜在健康风险。

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