Clerc Melodie M, Detzen Laurent, Vi-Fane Brigitte, Kerner Alexandra S, Garrec Pascal, Rignon-Bret Christophe, Jakubowicz Boris, Carra Maria-Clotilde, De La Dure-Molla Muriel, Fournier Benjamin P J, Kerner Stephane P
Resident, Department of Periodontology, U.F.R. of Odontology, Université Paris Cité, Reference Center for Oral and Dental Rare Diseases (O-Rares), Rothschild Hospital AP-HP, Paris, France.
Assistant Professor, Department of Periodontology, U.F.R. of Odontology, Université Paris Cité, Rothschild Hospital AP-HP, Paris, France.
J Prosthet Dent. 2025 Jul;134(1):50-60. doi: 10.1016/j.prosdent.2023.07.023. Epub 2023 Sep 9.
Cleft lip and palate are the most frequent congenital anomalies of the face and are often linked with lateral incisor agenesis. The therapeutic decision on whether and how to replace the lateral incisors is not straightforward, and a decision-making tree is needed.
The purpose of this systematic review was to evaluate the available literature reporting on treatments for the replacement of missing lateral incisors in cleft areas. By analyzing the success and survival rates of these treatments, a decision-making tree was developed.
The literature search was performed on the PubMed (MEDLINE), Web of Science, Cochrane, EMBASE, Dentistry of Oral and Science Source, and Google Scholar databases and was based on the question: Which treatment for patients with lateral incisor agenesis and cleft lip and palate has a good success rate?
Twenty-six articles were included in this systematic review. A meta-analysis was performed on 14 articles (20 case series, 6 case controls). The estimated overall 5-year survival rates were 96.4% for implant-supported prostheses.
Different treatment options are available, depending on the clinical situation. If the patient meets the conditions for implant placement, this treatment remains a preferred solution. If the prosthetic space is reduced, orthodontic space closure and composite resin restorations are possible. When these options are not possible, a resin-bonded fixed partial denture is the preferred option. If the teeth adjacent to the edentulous area require extensive restorations, a fixed partial denture may be a suitable alternative.
唇腭裂是最常见的面部先天性畸形，常与侧切牙缺失有关。关于是否以及如何替换侧切牙的治疗决策并非易事，因此需要一个决策树。
本系统评价的目的是评估有关唇腭裂区域缺失侧切牙替代治疗的现有文献报道。通过分析这些治疗的成功率和生存率，制定了一个决策树。
在PubMed（MEDLINE）、科学网、Cochrane、EMBASE、口腔科学来源牙科学数据库和谷歌学术数据库上进行文献检索，检索基于以下问题：哪种治疗方法对侧切牙缺失且伴有唇腭裂的患者成功率高？
本系统评价纳入了26篇文章。对14篇文章（20个病例系列，6个病例对照）进行了荟萃分析。种植体支持的修复体的5年总生存率估计为96.4%。
根据临床情况，有不同的治疗选择。如果患者符合种植体植入条件，这种治疗仍然是首选方案。如果修复空间减小，可以进行正畸关闭间隙和复合树脂修复。当这些选择不可行时，树脂粘结固定局部义齿是首选方案。如果无牙区相邻的牙齿需要广泛修复，固定局部义齿可能是一个合适的选择。
