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利奈唑胺致中毒性视神经病变。

Linezolid-Induced Toxic Optic Neuropathy.

机构信息

Department of Ophthalmology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

出版信息

Middle East Afr J Ophthalmol. 2021 Jan 19;27(4):235-237. doi: 10.4103/meajo.MEAJO_73_20. eCollection 2020 Oct-Dec.

Abstract

To report a case of linezolid-induced toxic optic neuropathy. Clinical examination and imaging are presented over a 4-month interval from initial presentation to subsequent follow-up of 4 months after discontinuation of linezolid. The patient was found to have optic neuropathy as demonstrated by clinical presentation and examination. Upon discontinuation of linezolid, the patient's visual acuity, visual fields, and color vision significantly improved. Linezolid has previously been reported to cause toxic optic neuropathy and retinopathy. We hereby describe a tuberculosis patient with linezolid-associated toxic optic neuropathy. Our report aims to describe the ocular side effects of linezolid use to enhance awareness.

摘要

报告 1 例利奈唑胺诱导的中毒性视神经病变。从初次就诊到停用利奈唑胺后 4 个月的后续随访,临床检查和影像学表现均进行了为期 4 个月的随访。患者被发现存在视神经病变,表现为临床症状和检查所见。停用利奈唑胺后,患者的视力、视野和色觉明显改善。利奈唑胺先前已被报道可引起中毒性视神经病变和视网膜病变。我们在此描述 1 例结核病患者发生与利奈唑胺相关的中毒性视神经病变。我们的报告旨在描述利奈唑胺使用的眼部副作用,以提高认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5713/7993054/e6cdfca149ea/MEAJO-27-235-g001.jpg

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