通过乳胶颗粒凝集法快速诊断B族链球菌Ⅲ型脑膜炎
Rapid diagnosis of type III group B streptococcal meningitis by latex particle agglutination.
作者信息
Edwards M S, Kasper D L, Baker C J
出版信息
J Pediatr. 1979 Aug;95(2):202-5. doi: 10.1016/s0022-3476(79)80651-4.
PMID:376808
Abstract
A latex particle agglutination assay was developed to detect type III group B streptococcal antigen in cerebrospinal fluid. Agglutination was observed in each of 12 initial and 54% of 26 subsequent CSF specimens obtained a mean of 53 hours after the institution of antimicrobial therapy. Latex agglutination was more sensitive than countercurrent immunoelectrophoresis for the detection of type III group B streptococcal antigen in CSF from neonates and young infants with meningitis.
摘要
开发了一种乳胶颗粒凝集试验以检测脑脊液中B族链球菌III型抗原。在抗菌治疗开始后平均53小时获得的12份初始脑脊液标本以及随后26份标本中的54%中均观察到凝集现象。对于检测患有脑膜炎的新生儿和幼儿脑脊液中的B族链球菌III型抗原，乳胶凝集试验比对流免疫电泳更敏感。
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