Department of Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Department of Operating Room of West China Hospital, West China School of Nursing, Sichuan University, Nursing Key Laboratory of Sichuan, Chengdu, Sichuan, China.
Medicine (Baltimore). 2023 Sep 8;102(36):e35087. doi: 10.1097/MD.0000000000035087.
In the present study, we analyzed the detection rate and related influencing factors of fatty liver in the health examination population in Chengdu area.
The case-control study was performed to compare the gender, age (years), body mass index (BMI), smoking, drinking, abnormal lipid metabolism, hypertension, hyperglycemia, hyperuricemia Is there any statistically significant difference in the detection rate of diseases such as metabolic syndrome, and logistic regression analysis is conducted to analyze the comprehensive impact of each influencing factor on the prevention of fatty liver disease.
Among 14,426 survey subjects, a total of 6717 patients with fatty liver were detected, with a detection rate of 47.22%. There are significant differences in the incidence of fatty liver disease among different gender groups, with the incidence rate in males being significantly higher than that in females (P < .05); The incidence of fatty liver in elderly subjects was significantly higher than that in middle-aged and young subjects (P < .05); The prevalence rate of individuals with a BMI > 24 was significantly higher than that of individuals with a BMI < 24 (P < .05). The prevalence of fatty liver in the population with abnormal lipid metabolism, hypertension, hyperglycemia, hyperuricemia, metabolic syndrome and other diseases was significantly higher (P < .05); After stratified analysis by gender and age, the incidence of fatty liver in males was significantly higher than that in females in the 3 age groups < 60 years old (P < .05); In the age group ≥ 60 years old, the difference in the incidence of fatty liver disease between males and females was significantly reduced, and the difference was not statistically significant (P > .05).
The health screening of patients with fatty liver should be carried out regularly, and attention should be paid to the intervention and prevention of overweight people and people with basal metabolism diseases such as hyperglycemia and hypertension, so as to reduce the incidence of fatty liver.
本研究分析了成都地区健康体检人群中脂肪肝的检出率及相关影响因素。
采用病例对照研究，比较了性别、年龄（岁）、体质量指数（BMI）、吸烟、饮酒、脂代谢异常、高血压、高血糖、高尿酸血症、代谢综合征等疾病的检出率，对各影响因素综合作用于脂肪肝发病的情况进行 logistic 回归分析。
在 14426 名调查对象中，共检出脂肪肝患者 6717 例，检出率为 47.22%。不同性别组脂肪肝疾病的发生率差异有统计学意义，男性的发生率明显高于女性（P <.05）；高龄组的脂肪肝发生率明显高于中、青年组（P <.05）；BMI>24 者的检出率明显高于 BMI<24 者（P <.05）。脂代谢异常、高血压、高血糖、高尿酸血症、代谢综合征等疾病人群的脂肪肝检出率明显升高（P <.05）；经性别和年龄分层分析后，在 3 个年龄组<60 岁的人群中，男性的脂肪肝发生率明显高于女性（P <.05）；在年龄组≥60 岁的人群中，男性和女性的脂肪肝疾病发生率差异减小，差异无统计学意义（P >.05）。
应对脂肪肝患者进行定期健康筛查，重视超重人群及高血糖、高血压等基础代谢性疾病人群的干预和预防，降低脂肪肝的发病率。
