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新生儿重症监护病房中的谵妄

Delirium in the NICU.

机构信息

University of Utah School of Medicine, Department of Pediatrics, Division of Neonatology, Salt Lake City, UT, USA.

University of Utah School of Medicine, Department of Pediatrics, Division of Pediatric Behavioral Health and Psychiatry, Salt Lake City, UT, USA.

出版信息

J Perinatol. 2024 Feb;44(2):157-163. doi: 10.1038/s41372-023-01767-5. Epub 2023 Sep 8.

DOI:10.1038/s41372-023-01767-5
PMID:37684547
Abstract

Delirium in the NICU is an underrecognized phenomenon in infants who are often complex and critically ill. The current understanding of NICU delirium is developing and can be informed by adult and pediatric literature. The NICU population faces many potential risk factors for delirium, including young age, developmental delay, mechanical ventilation, severe illness, and surgery. There are no diagnostic tools specific to infants. The mainstay of delirium treatment is to treat the underlying cause, address modifiable risk factors, and supportive care. This review will summarize current knowledge and areas where more research is needed.

摘要

新生儿重症监护病房(NICU)中的谵妄是一种在经常处于复杂和危重状态的婴儿中未被充分认识的现象。目前对 NICU 谵妄的理解正在发展,并可以借鉴成人和儿科文献。NICU 人群面临许多谵妄的潜在危险因素,包括年龄小、发育迟缓、机械通气、重病和手术。目前尚无针对婴儿的特定诊断工具。谵妄治疗的主要方法是治疗根本原因、处理可改变的危险因素和支持性护理。本综述将总结当前的知识和需要进一步研究的领域。

相似文献

1
Delirium in the NICU.新生儿重症监护病房中的谵妄
J Perinatol. 2024 Feb;44(2):157-163. doi: 10.1038/s41372-023-01767-5. Epub 2023 Sep 8.
2
Delirium in the NICU: Risk or Reality?新生儿重症监护病房中的谵妄:风险还是现实?
Neonatal Netw. 2021 Mar 1;40(2):103-112. doi: 10.1891/0730-0832/11-T-727.
3
Delirium and Mortality in Critically Ill Children: Epidemiology and Outcomes of Pediatric Delirium.危重症患儿的谵妄与死亡率:小儿谵妄的流行病学及转归
Crit Care Med. 2017 May;45(5):891-898. doi: 10.1097/CCM.0000000000002324.
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[Development and treatment of delirium in critically ill children].[危重症儿童谵妄的发生与治疗]
Ugeskr Laeger. 2012 Jan 30;174(5):270-5.
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Delirium in the NICU: A Point Prevalence Study.新生儿重症监护病房谵妄:一项时点患病率研究。
Hosp Pediatr. 2021 Nov;11(11):e321-e326. doi: 10.1542/hpeds.2020-005736.
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The intensive care delirium research agenda: a multinational, interprofessional perspective.重症监护谵妄研究议程:多国家、多专业视角。
Intensive Care Med. 2017 Sep;43(9):1329-1339. doi: 10.1007/s00134-017-4860-7. Epub 2017 Jun 13.
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Pediatric delirium: monitoring and management in the pediatric intensive care unit.儿科谵妄:儿科重症监护病房的监测与管理。
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Detection and Management of Delirium in the Neonatal Unit: A Case Series.新生儿单元中谵妄的检测和管理:病例系列。
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Pediatr Clin North Am. 2017 Oct;64(5):1117-1132. doi: 10.1016/j.pcl.2017.06.009.
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A Delirium Prevention and Management Initiative: Implementing a Best Practice Recommendation for the NICU.一项谵妄预防与管理倡议:为新生儿重症监护病房实施最佳实践建议
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Non-pharmacological interventions for delirium in critically ill children: a scoping review.危重症儿童谵妄的非药物干预措施:一项范围综述
BMJ Open. 2025 Sep 2;15(9):e094529. doi: 10.1136/bmjopen-2024-094529.
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Refractory agitation in the NICU: challenges in prevention, diagnosis, and treatment.新生儿重症监护病房中的难治性躁动:预防、诊断及治疗中的挑战
Front Pediatr. 2025 Feb 27;13:1504619. doi: 10.3389/fped.2025.1504619. eCollection 2025.
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Implementing Screening for Neonatal Delirium in the Neonatal Intensive Care Unit: A Quality Improvement Initiative.

本文引用的文献

1
Factors Associated With Delirium in Children: A Systematic Review and Meta-Analysis.与儿童谵妄相关的因素:系统评价和荟萃分析。
Pediatr Crit Care Med. 2023 May 1;24(5):372-381. doi: 10.1097/PCC.0000000000003196. Epub 2023 Feb 15.
2
Pediatric Delirium and All-Cause PICU Readmissions Within 1 Year.儿科谵妄与一年内所有原因 PICU 再入院。
Pediatr Crit Care Med. 2022 Oct 1;23(10):766-773. doi: 10.1097/PCC.0000000000003037. Epub 2022 Jul 27.
3
Delirium in the Neonate.新生儿谵妄
在新生儿重症监护病房实施新生儿谵妄筛查:一项质量改进计划。
Pediatr Qual Saf. 2024 Oct 21;9(6):e752. doi: 10.1097/pq9.0000000000000752. eCollection 2024 Nov-Dec.
Clin Perinatol. 2022 Mar;49(1):1-14. doi: 10.1016/j.clp.2021.11.001. Epub 2022 Jan 21.
4
Implementation of a Delirium Bundle for Pediatric Intensive Care Patients.针对儿科重症监护患者实施谵妄护理包。
Front Pediatr. 2022 Feb 7;10:826259. doi: 10.3389/fped.2022.826259. eCollection 2022.
5
Delirium in the NICU: A Point Prevalence Study.新生儿重症监护病房谵妄:一项时点患病率研究。
Hosp Pediatr. 2021 Nov;11(11):e321-e326. doi: 10.1542/hpeds.2020-005736.
6
Health-Related Quality of Life Following Delirium in the PICU.儿科重症监护病房谵妄后健康相关生活质量。
Pediatr Crit Care Med. 2022 Feb 1;23(2):118-128. doi: 10.1097/PCC.0000000000002813.
7
Prospective Validation of the Preschool Confusion Assessment Method for the ICU to Screen for Delirium in Infants Less Than 6 Months Old.前瞻性验证 ICU 幼儿谵妄评估方法对 6 个月以下婴儿谵妄的筛查作用。
Crit Care Med. 2021 Oct 1;49(10):e902-e909. doi: 10.1097/CCM.0000000000005099.
8
Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain.阿片类药物的使用会增加危重症成人发生谵妄的风险,与疼痛无关。
Am J Respir Crit Care Med. 2021 Sep 1;204(5):566-572. doi: 10.1164/rccm.202010-3794OC.
9
The Burden of Antipsychotic-Induced Weight Gain and Metabolic Syndrome in Children.儿童抗精神病药物所致体重增加及代谢综合征的负担
Front Psychiatry. 2021 Mar 12;12:623681. doi: 10.3389/fpsyt.2021.623681. eCollection 2021.
10
Delirium in the NICU: Risk or Reality?新生儿重症监护病房中的谵妄:风险还是现实?
Neonatal Netw. 2021 Mar 1;40(2):103-112. doi: 10.1891/0730-0832/11-T-727.