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急性A型主动脉夹层患者主动脉全腔内修复的可行性:119例患者的形态学分析

Feasibility of Total Endovascular Repair of the Aorta in Patients with Acute Type A Aortic Dissection: Morphological Analysis of 119 Patients.

作者信息

Ahmad Wael, Liebezeit-Sievert Mark, Wegner Moritz, Alokhina Anastasiia, Wahlers Thorsten, Dorweiler Bernhard, Luehr Maximilian

机构信息

Department of Vascular and Endovascular Surgery, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.

Department of Cardiothoracic Surgery, Heart Centre, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.

出版信息

J Clin Med. 2023 Aug 28;12(17):5615. doi: 10.3390/jcm12175615.

Abstract

(1) Background: This study aimed to morphologically analyze acute type A aortic dissection (aTAAD) patients for potential endovascular treatment candidates. The objective was to specify requirements for aTAAD endovascular devices. (2) Methods: A single-center retrospective analysis included aTAAD patients who underwent open surgical repair between November 2005 and December 2020. Preoperative CTA scans were used for morphological analysis, assessing endovascular repair eligibility. Statistical tests were performed. (3) Results: A total of 129 patients with aTAAD were studied, with 119 included. Entry tear (ET) locations were identified, mainly in the aortic root, 20 mm above the sinotubular junction (STJ) and within the ascending aorta (20 mm above STJ to -20 mm before the brachiocephalic trunk). Endovascular treatment was deemed feasible for 36 patients, with suggested solutions for the aortic arch and descending aorta. Significant differences were observed between eligible and noneligible groups for aortic diameter, false lumen diameter, distance between STJ and entry tear, and more. Dissection extension showed no significant difference. (4) Conclusions: Morphological analysis identified potential aTAAD candidates for endovascular treatment, highlighting differences between eligible and noneligible morphologies. This study offers insights for implementing endovascular approaches in aTAAD treatment and emphasizes the need for research and standardized protocols.

摘要

(1) 背景:本研究旨在对急性A型主动脉夹层(aTAAD)患者进行形态学分析,以筛选可能适合血管内治疗的患者。目的是明确aTAAD血管内治疗器械的要求。(2) 方法:一项单中心回顾性分析纳入了2005年11月至2020年12月期间接受开放手术修复的aTAAD患者。术前CTA扫描用于形态学分析,评估血管内修复的适用性。进行了统计学检验。(3) 结果:共研究了129例aTAAD患者,其中119例纳入分析。确定了入口撕裂(ET)的位置,主要位于主动脉根部、窦管交界(STJ)上方20 mm处以及升主动脉内(STJ上方20 mm至头臂干前方-20 mm之间)。36例患者被认为可行血管内治疗,并针对主动脉弓和降主动脉提出了相应解决方案。在符合条件和不符合条件的组之间,观察到主动脉直径、假腔直径、STJ与入口撕裂之间的距离等存在显著差异。夹层扩展无显著差异。(4) 结论:形态学分析确定了可能适合血管内治疗的aTAAD患者,突出了符合条件和不符合条件形态之间的差异。本研究为在aTAAD治疗中实施血管内方法提供了见解,并强调了研究和标准化方案的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/199f/10488701/c4fd184cc189/jcm-12-05615-g001.jpg

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