左心室射血分数降低（<50%）患者行旋磨术的安全性及长期预后（旋磨术-射血分数降低研究）
Safety and Long-Term Outcomes of Rotablation in Patients with Reduced (<50%) Left Ventricular Ejection Fraction (rEF) (The Rota-REF Study).
作者信息
Ayoub Mohamed, Tajti Péter, Akin Ibrahim, Behnes Michael, Schupp Tobias, Forner Jan, Omran Hazem, Westermann Dirk, Rudolph Volker, Mashayekhi Kambis
机构信息
Clinic for General and Interventional Cardiology/Angiology, Heart and Diabetes Center NRW, Ruhr University Bochum, 32545 Bad Oeynhausen, Germany.
Gottsegen György National Cardiovascular Center, 1096 Budapest, Hungary.
出版信息
J Clin Med. 2023 Aug 30;12(17):5640. doi: 10.3390/jcm12175640.
Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database. The primary endpoint was in-hospital major adverse cardiovascular and cerebral events (MACCE). The secondary endpoint was 3-year MACCE. In-hospital MACCE rates were significantly higher in RA-PCI compared to standard PCI without RA (PCI) (7.6% vs. 3.9%, = 0.0009). However, 3-years MACCE rates were similar in RA-PCI and PCI (26.40% vs. 26.6%, = 0.948). In conclusion, RA-PCI in patients with rEF is feasible, safe, and shows similar long-term results to PCI.
对于接受经皮冠状动脉介入治疗（PCI）的左心室收缩功能降低患者，旋磨术（RA）的临床结局仍研究不足。我们的研究旨在评估RA-PCI对左心室收缩功能障碍患者长期结局的影响。2015年至2019年期间，医院数据库纳入了4941例接受PCI（有或无RA）的左心室功能降低（rEF）患者。主要终点是院内主要不良心血管和脑血管事件（MACCE）。次要终点是3年MACCE。与无RA的标准PCI（PCI）相比，RA-PCI的院内MACCE发生率显著更高（7.6%对3.9%，P = 0.0009）。然而，RA-PCI和PCI的3年MACCE发生率相似（26.40%对26.6%，P = 0.948）。总之，rEF患者的RA-PCI是可行、安全的，并且与PCI显示出相似的长期结果。
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