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气道微生物群:环境暴露与呼吸健康的联系。

Airway microbiome: environmental exposure-respiratory health nexus.

作者信息

Gangneux Jean-Pierre, Rhodes Johanna L, Papon Nicolas

机构信息

Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France; Laboratory of Parasitology and Medical Mycology, European Confederation of Medical Mycology (ECMM) Excellence Center, Centre National de Référence Aspergilloses Chroniques, Rennes Teaching Hospital, F-35000 Rennes, France.

MRC Centre for Global Infectious Disease Analysis, Imperial College School of Public Health, Imperial College London, South Kensington, London SW7 2BX, UK; Department of Medical Microbiology, Radboudumc, Nijmegen, The Netherlands.

出版信息

Trends Mol Med. 2023 Nov;29(11):875-877. doi: 10.1016/j.molmed.2023.08.011. Epub 2023 Sep 8.

Abstract

Toxicants such as smoke, biofuel, and pollutants constantly challenge our respiratory health, but little is known about the pathophysiological processes involved. In a new report, Lin et al. provide evidence that our bacterial and fungal lung populations orchestrate the interplay between environmental exposure and lung functions, thereby conditioning health outcomes.

摘要

烟雾、生物燃料和污染物等有毒物质不断威胁着我们的呼吸健康,但对于其中涉及的病理生理过程却知之甚少。在一项新报告中,林等人提供了证据,表明我们肺部的细菌和真菌群落协调着环境暴露与肺功能之间的相互作用,从而决定健康结果。

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