Boumaza-Hamladji Sarah, Benhabyles Narimen, Toubal Souheyla, El Haddad Djillali, Bouchenak Ouahiba, Bellalemi Nerdjes, Berrichi Drifa, Meziani Ibtissem
Département de Biologie, Faculté Des Sciences, Université M'Hamed Bougara de Boumerdes, Boumerdès, Algérie.
J Adv Pharm Technol Res. 2023 Jul-Sep;14(3):191-195. doi: 10.4103/JAPTR.JAPTR_126_23. Epub 2023 Jul 28.
The objective of this study is to fight against antibiotic resistance, especially in urinary tract infection. To limit the spread of this scourge, we have proposed the use of flavonoid extract of the medicinal plant against pathogenic bacteria of urinary tract infections. , was introduced in the arid regions of the Algerian Sahara for sustainable rural development in Algeria. The phytochemical study, revealed the presence of a multitude of metabolites. The yield of aqueous extract is 27.35% ± 1.95 and flavonoid concentration is 38.59 ± 0.002 mg EQ/gE. The high-performance liquid chromatography revealed the presence of 47 compounds, the most important of which are ascorbic acid (16.82%) and luteolin-7-Glycoside (26.8%). The aqueous extract has very significant antibacterial activity with an inhibition zone varying between 26.2 ± 0.25 (mm) for and 12.66 ± 1.15 for .
本研究的目的是对抗抗生素耐药性，尤其是在尿路感染方面。为了限制这种祸害的传播，我们提议使用药用植物的黄酮类提取物来对抗尿路感染的病原菌。该提取物已被引入阿尔及利亚撒哈拉的干旱地区，以促进阿尔及利亚农村的可持续发展。植物化学研究表明存在多种代谢物。水提取物的产率为27.35%±1.95，黄酮类化合物浓度为38.59±0.002毫克当量/克提取物。高效液相色谱显示存在47种化合物，其中最重要的是抗坏血酸（16.82%）和木犀草素-7-糖苷（26.8%）。水提取物具有非常显著的抗菌活性，抑菌圈在[具体细菌1]的26.2±0.25（毫米）和[具体细菌2]的12.66±1.15之间变化。
