Tona L, Kambu K, Ngimbi N, Cimanga K, Vlietinck A J
Faculty of Pharmacy, University of Kinshasa, Congo.
J Ethnopharmacol. 1998 May;61(1):57-65. doi: 10.1016/s0378-8741(98)00015-4.
Results from the in vitro antiamoebic activity of some Congolese plant extracts used as antidiarrhoeic in traditional medicine indicated that of 45 plant extracts tested, 35 (77.78%) exhibited an antiamoebic activity and 10 (22.22%) were inactive. The highest activity (MIC < 100 microg/ml) was obtained with extracts from root bark of Paropsia brazzeana, Cryptolepis sanguinolenta, Alchornea cordifolia, Hensia pulchella, Maprounea africana, Rauwolfia obscura and Voacanga africana, leaves and stem bark of Psidium guajava, stem bark of Dialum englerianum, Harungana madagascariensis and Mangifera indica, mature seeds of Carica papaya, and leaves of Morinda morindoides and Tithonia diversifolia. Metronidazole used as reference product showed a more pronounced activity than that of all plant extracts tested.
一些在传统医学中用作抗腹泻药的刚果植物提取物的体外抗阿米巴活性结果表明，在测试的45种植物提取物中，35种（77.78%）表现出抗阿米巴活性，10种（22.22%）无活性。巴西帕罗普西亚、红血藤、心叶海漆、美丽亨氏藤、非洲马普藤、暗色萝芙木和非洲沃坎加的根皮提取物，番石榴叶和茎皮提取物，恩格勒迪亚卢姆、马达加斯加哈伦加那和芒果的茎皮提取物，番木瓜成熟种子提取物，以及巴戟天和肿柄菊叶提取物的活性最高（最低抑菌浓度<100微克/毫升）。用作参考产品的甲硝唑显示出比所有测试植物提取物更显著的活性。
