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孕期输尿管镜检查:挪威一家三级医疗中心40多年来的结果与经验教训

Ureteroscopy during pregnancy: Outcomes and lessons learned over 4 decades at a tertiary center in Norway.

作者信息

Juliebø-Jones Patrick, Beisland Christian, Gjengstø Peder, Baug Stephen, Ulvik Øyvind

机构信息

Department of Urology, Haukeland University Hospital, Bergen, Norway.

Department of Clinical Medicine, University of Bergen, Bergen, Norway.

出版信息

Curr Urol. 2023 Mar;17(1):7-12. doi: 10.1097/CU9.0000000000000157. Epub 2022 Oct 8.

Abstract

BACKGROUND

The management of suspected kidney stone disease in pregnancy is challenging. In cases of persistent flank pain and where investigations may have rendered equivocal results, ureteroscopy (URS) is a recognized diagnostic and therapeutic intervention. This study aimed to investigate the safety and outcomes associated with performing URS during pregnancy, as the technique has evolved over the past 4 decades at our center.

MATERIALS AND METHODS

We performed a retrospective analysis of pregnant patients who underwent URS at our tertiary center between 1984 and 2022. Outcomes of interest included anesthetic approach, operative time, hospital stay, and complications.

RESULTS

Eighty-seven pregnant patients underwent 96 URS procedures, and 60% ( = 57) of these procedures were performed during the third trimester. Overall, 58% (n = 56) of the procedures were achieved with local anesthesia and light sedation. During the most recent decade, the latter was successfully carried out in 97% of the procedures, with the remainder occurring under spinal anesthesia as per patient choice. Overall, 57% (n = 50) of the whole study group had ureteral calculi found at the time of surgery and in 88% (n = 44) of these cases, fragmentation/extraction was performed. The remainder had insertion of ureteral stent with definitive clearance deferred until postpartum. Mean operative time and postprocedure hospital stay was 33 minutes (range, 7-100 minutes) and 2.2 days (range, 0-16 days), respectively. The overall intraoperative and postoperative complication rates were 2% and 11%, respectively. During the final decade, the latter improved to 6% and all adverse events were minor (Clavien I/II), with the exception of a single case. Regarding exit strategy, ureteral stent was placed in 42% (n = 40) of the procedures, 23% (n = 22) had ureteral catheter inserted, and the remainder (35%, n = 34) had none.

CONCLUSIONS

Ureteroscopy can be safely performed during pregnancy using anesthetic approach with local anesthesia and light sedation. Development of a local protocol and multidisciplinary management algorithm are instrumental in enabling the delivery of such a service.

摘要

背景

妊娠期疑似肾结石疾病的管理具有挑战性。在持续性胁腹疼痛且检查结果可能不明确的情况下,输尿管镜检查(URS)是一种公认的诊断和治疗干预措施。本研究旨在调查在妊娠期进行URS的安全性及相关结果,因为该技术在我们中心过去40年里不断发展。

材料与方法

我们对1984年至2022年期间在我们三级中心接受URS的孕妇进行了回顾性分析。感兴趣的结果包括麻醉方式、手术时间、住院时间和并发症。

结果

87名孕妇接受了96次URS手术,其中60%(n = 57)的手术在妊娠晚期进行。总体而言,58%(n = 56)的手术采用局部麻醉和轻度镇静完成。在最近十年中,97%的手术成功采用了后者,其余根据患者选择在脊髓麻醉下进行。总体而言,整个研究组中57%(n = 50)在手术时发现输尿管结石,其中88%(n = 44)的病例进行了碎石/取石。其余患者插入输尿管支架,确定性清除推迟至产后。平均手术时间和术后住院时间分别为33分钟(范围7 - 100分钟)和2.2天(范围0 - 16天)。总体术中及术后并发症发生率分别为2%和11%。在最后十年中,后者降至6%,除1例例外,所有不良事件均为轻微(Clavien I/II级)。关于出院策略,42%(n = 40)的手术放置了输尿管支架,23%(n = 22)插入了输尿管导管,其余(35%,n = 34)未采取任何措施。

结论

在妊娠期使用局部麻醉和轻度镇静的麻醉方式可安全地进行输尿管镜检查。制定当地方案和多学科管理算法有助于提供此类服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f49b/10487287/eb54242e71cf/curr-urol-17-07-g001.jpg

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