Nakashima T, Sano A, Seto Y, Nakajima T, Nakagawa Y, Okuno T, Takino T, Hasegawa T
Clin Chim Acta. 1986 Oct 15;160(1):47-53. doi: 10.1016/0009-8981(86)90334-7.
The urinary bile acids of 20 adults (aged between 20 and 40 yr), 17 neonates (below 1 week old) and 15 aged men (older than 80 yr old) who were all healthy, were analyzed by gas-liquid chromatography and gas-liquid chromatography-mass spectrometry. Frequently, three unusual trihydroxy bile acids, namely hyocholic acid, ursocholic acid and omega-muricholic acid were detected as minor components. Our data further suggest that the metabolism of unusual trihydroxy bile acids in the healthy humans is related to age.
对20名健康成年人（年龄在20至40岁之间）、17名新生儿（1周龄以下）和15名老年男性（80岁以上）的尿胆汁酸进行了气液色谱和气液色谱-质谱分析。经常检测到三种不常见的三羟基胆汁酸，即猪胆酸、熊去氧胆酸和ω-鼠胆酸作为次要成分。我们的数据进一步表明，健康人体内不常见的三羟基胆汁酸代谢与年龄有关。
